Results 221 to 230 of about 140,016 (274)

Caspase‐6 Controls Lipid and Energy Metabolism in Diet‐Induced Obesity

Advanced Science, Volume 13, Issue 21, 13 April 2026.
This study reveals an unknown metabolic role of caspase‐6 beyond cell death. Caspase‐6 deficiency protects against HFD‐induced obesity by increasing energy expenditure, reducing inflammation, and improving glucose metabolism. Mechanistically, caspase‐6 cleaves PPARγ and SP1 to suppress ATGL expression.
Abhishek Gupta, Wenjing You, Linmeng Han, Jianfei Ji, Meixia Pan, Xianlin Han, Xiaoli Sun, Peng Zhao   +7 more
wiley   +1 more source

Multidimensional Analysis of Serum Adiponectin, Leptin, and Resistin Levels and Their Correlation with Childhood Obesity Based on Gut Microbiota and Inflammatory Markers: A Single-Center Cross-Sectional Retrospective Study. [PDF]

Int J Gen Med
Wang X, Wu Y, Zhang X.
europepmc   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, Volume 13, Issue 23, 23 April 2026.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

MyD88 Inhibition Ameliorates Diabetes-Induced Hepatic Inflammation and Gluconeogenesis Through Adipose IL-10 Induction. [PDF]

Int J Mol Sci
Li YC, Lai HC, Chen PH, Tang CH, Chen LW.   +4 more
europepmc   +1 more source

Adipocytes in Aortic Stenosis: Association With Clinical and Morphological Indices

Clinical Anatomy, Volume 39, Issue 3, Page 325-331, April 2026.
ABSTRACT Recently, great attention has been given to understanding the new pathogenetic mechanisms underlying aortic stenosis (AS). The study aims to understand the role of mature adipocytes in AS and their association with histologic, clinical, and echocardiographic data, an area previously overlooked in AS research.
Elena Zoico, Tanaz Saatchi, Silvia Urbani, Vanni Rizzatti, Gloria Mazzali, Francesco Fantin, Silvia Faccioli, Alessandro Gavras, Mauro Zamboni, Anna Giani   +9 more
wiley   +1 more source

Cross-Sectional and Longitudinal Associations of Irisin and Adiponectin With Obesity, Sarcopenia and Sarcopenic Obesity. [PDF]

J Cachexia Sarcopenia Muscle
Kim Y, Song HJ, Kim DH, Jeong JY, Park KH, Park YS, Kim JK, Noh HM.   +7 more
europepmc   +1 more source

Linking Targeted Pancreatic Cancer Genes With Metabolic Disorders: A Cross‐Species Translational Pathway

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Introduction Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies because of its typically late diagnosis and limited treatment options, with surgical resection being the primary intervention. Emerging studies have consistently reported associations between PDAC and metabolic dysfunctions, including obesity ...
Dipanwita Nath, Caitlin Ditchfield, Joshua Price, Shivan Sivakumar, Simon W. Jones, Animesh Acharjee   +5 more
wiley   +1 more source

T‑cadherin and its impact on human diseases (Review). [PDF]

Mol Med Rep
Song Y, Wang X, Bian Y.
europepmc   +1 more source

<i>Adipokines and Cardiometabolic Risk in South Asian Americans: Findings from the MASALA Study</i>. [PDF]

Am J Prev Cardiol
Uttarwar S, Shah NS, Kanaya AM, Gadgil MD.   +3 more
europepmc   +1 more source

Adiponectin (ADIPOQ); adiponectin receptor 1 (ADIPOR1); ADIPOR2 [PDF]

Science-Business eXchange, 2013
openaire   +1 more source