Results 121 to 130 of about 84,802 (258)

Adipose-targeted microneedle patch co-delivering semaglutide and rosiglitazone unlocks adipose browning efficacy for obesity therapy

Nano Research
Current clinical management of obesity relies primarily on glucagon-like peptide-1 (GLP-1) receptor agonists or peroxisome proliferator-activated receptor gamma (PPAR-γ) agonists. However, GLP-1 agonists often lead to weight regain after discontinuation,
Weiqin Yao, Jiawen Wang, Xuan Zeng, Weihai Chen, Xianzheng Zhang   +4 more
doaj   +1 more source

The pelvis doesn't walk by itself: Wider pelves reduce the cost of walking over unstable surfaces

The Anatomical Record, EarlyView.
Abstract Walking over variable and/or unstable terrain is a key aspect of daily life and was crucial to the evolution of bipedalism. The ability to find gait solutions that maintained stability over uneven terrain for the least increase in metabolic cost was likely a hallmark of locomotor effectiveness in early humans, in particular acting as an ...
Cara Wall‐Scheffler, Taylor Morscheck, Katelyn McCollor   +2 more
wiley   +1 more source

Residual HIV activity and host immunometabolic remodeling during antiretroviral therapy: implications for cardiovascular–kidney–metabolic risk

Frontiers in Immunology
Antiretroviral therapy (ART) suppresses productive HIV replication but does not eliminate viral persistence, residual transcription, or host immune perturbation.
Jiahui Zhang, Xuanlan Li, Chen Chen, Zhuoyan Wu, Fengping Qin, Yuxuan Li, Yun Zhang, Chuanyi Ning, Chuanyi Ning, Chuanyi Ning   +9 more
doaj   +1 more source

Interrelationships among age at adiposity rebound, BMI during childhood, and BMI after age 14 years in an electronic health record database. [PDF]

Obesity (Silver Spring), 2022
Freedman DS, Goodwin-Davies AJ, Kompaniyets L, Lange SJ, Goodman AB, Phan TT, Rao S, Eneli I, Forrest CB.   +8 more
europepmc   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Association between perinatal factors, genetic susceptibility to obesity and age at adiposity rebound in children of the EDEN mother-child cohort. [PDF]

Int J Obes (Lond), 2021
Cissé AH, Lioret S, de Lauzon-Guillain B, Forhan A, Ong KK, Charles MA, Heude B.   +6 more
europepmc   +1 more source

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

Weight, height and body mass index nomograms; early adiposity rebound in a sample of children in Tehran, Iran

International Journal of Preventive Medicine, 2013
Background: Assessing growth is a useful tool for defining health and nutritional status of children. The objective of this study was to construct growth reference curves of Iranian infants and children (0-6 years old) and compare them with previous and ...
Mostafa Hosseini, Iman Navidi, Bahare Hesamifard, Mahmoud Yousefifard, Nasim Jafari, Sakine Ranji Poorchaloo, Neamatollah Ataei   +6 more
doaj  

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Adiposity in British secondary school children: a population based study

, 2008
Summary:Adiposity is defined as the property of containing fat. Excessive adiposity is a cause of both morbidity and mortality in adults. Important consequences include increased risks of type 2 diabetes, coronary heart disease and stroke, (particularly ...
Odoki, Katherine Helen
core   +1 more source