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The adipose organ: morphological perspectives of adipose tissues [PDF]

Proceedings of the Nutrition Society, 2001
Anatomically, an organ is defined as a series of tissues which jointly perform one or more interconnected functions. The adipose organ qualifies for this definition as it is made up of two tissue types, the white and brown adipose tissues, which collaborate in partitioning the energy contained in lipids between thermogenesis and the other metabolic ...
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Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation

Molecular Metabolism, 2017
Objective: Several studies have demonstrated anti-diabetic and anti-obesogenic properties of visceral adipose tissue-derived serine protease inhibitor (vaspin) and so evoked its potential use for treatment of obesity-related diseases.
Juliane Weiner, Kerstin Rohde, Kerstin Krause, Konstanze Zieger, Nora Klöting, Susan Kralisch, Peter Kovacs, Michael Stumvoll, Matthias Blüher, Yvonne Böttcher, John T. Heiker   +10 more
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Associations of fatty acids composition and estimated desaturase activities in erythrocyte phospholipids with biochemical and clinical indicators of cardiometabolic risk in non-diabetic Serbian women: the role of level of adiposity

Frontiers in Nutrition, 2023
IntroductionFatty acids (FAs) composition and desaturase activities can be altered in different metabolic conditions, but the adiposity-independent associations with clinical and biochemical indicators of cardiometabolic risk are still unclear.
Ivana Šarac, Jasmina Debeljak-Martačić, Marija Takić, Vuk Stevanović, Jelena Milešević, Milica Zeković, Tamara Popović, Jovica Jovanović, Nevena Kardum Vidović   +8 more
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Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men [PDF]

Diabetes & Metabolism Journal, 2020
BackgroundSouth Asians generally have an unfavourable metabolic phenotype compared with white Caucasians, including central obesity and insulin resistance.
Laura G.M. Janssen, Andrea D. van Dam, Mark J.W. Hanssen, Sander Kooijman, Kimberly J. Nahon, Hanneke Reinders, Ingrid M. Jazet, Wouter D. van Marken Lichtenbelt, Patrick C.N. Rensen, Natasha M. Appelman-Dijkstra, Mariëtte R. Boon   +10 more
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Positive Impacts of Aphanizomenon Flos Aquae Extract on Obesity-Related Dysmetabolism in Mice with Diet-Induced Obesity

Cells, 2023
The present study evaluated the ability of KlamExtra®, an Aphanizomenon flos aquae (AFA) extract, to counteract metabolic dysfunctions due to a high fat diet (HFD) or to accelerate their reversion induced by switching an HFD to a normocaloric diet in ...
Simona Terzo, Pasquale Calvi, Marta Giardina, Giacoma Gallizzi, Marta Di Carlo, Domenico Nuzzo, Pasquale Picone, Roberto Puleio, Flavia Mulè, Stefano Scoglio, Antonella Amato   +10 more
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Childhood Adiposity, Adult Adiposity, and Cardiovascular Risk Factors

New England Journal of Medicine, 2011
Obesity in childhood is associated with increased cardiovascular risk. It is uncertain whether this risk is attenuated in persons who are overweight or obese as children but not obese as adults.We analyzed data from four prospective cohort studies that measured childhood and adult body-mass index (BMI, the weight in kilograms divided by the square of ...
Juonala, M, Magnussen, CG, Berenson, GS, Venn, A, Burns, TL, Sabin, MA, Srinivasan, SR, Daniels, SR, Davis, PH, Chen, W, Sun, C, Cheung, M, Viikari, JSA, Dwyer, T, Raitakari, OT   +14 more
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Epigenetic age acceleration is associated with speed of pubertal growth but not age of pubertal onset

Scientific Reports
Using data from a longitudinal cohort of children, we examined whether epigenetic age acceleration (EAA) was associated with pubertal growth and whether these associations were mediated by adiposity.
Catherine Kim, Kylie K. Harrall, Deborah H. Glueck, Christine Hockett, Dana Dabelea   +4 more
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Cardiac Concomitants of Feedback and Prediction Error Processing in Reinforcement Learning

Frontiers in Neuroscience, 2017
Successful learning hinges on the evaluation of positive and negative feedback. We assessed differential learning from reward and punishment in a monetary reinforcement learning paradigm, together with cardiac concomitants of positive and negative ...
Lucas Kastner, Lucas Kastner, Jana Kube, Jana Kube, Jana Kube, Arno Villringer, Arno Villringer, Arno Villringer, Arno Villringer, Jane Neumann, Jane Neumann, Jane Neumann   +11 more
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(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distributionResearch in context

EBioMedicine, 2019
Background: In brain, CREB-regulated transcription co-activator 1 (CRTC1) is involved in metabolic dysregulation. In humans a SNP in CRTC1 was associated to body fat percentage and two SNPs affected RNA Pol II binding and chromatin structure, implying ...
Kerstin Rohde, Maria Keller, Lars la Cour Poulsen, Torunn Rønningen, Michael Stumvoll, Anke Tönjes, Peter Kovacs, Annette Horstmann, Arno Villringer, Matthias Blüher, Yvonne Böttcher   +10 more
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Efficacy of DiaLife, an education program for relatives of adult patients with diabetes – study protocol of a cluster randomized controlled trial

Trials, 2019
Background The global prevalence of diabetes mellitus (DM) has been increasing over recent decades. In Germany, the prevalence for DM type 1 and type 2 in adults is estimated at about 7.7%.
M. Bernard, N. Müller, L. Hecht, G. Fabisch, A. Harder, C. Luck-Sikorski   +5 more
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