Results 21 to 30 of about 139,622 (267)
Frontiers in Neuroscience, 2012 The Iowa Gambling Task (IGT) has been widely used to assess differences in decision-making under uncertainty. Recently, several studies have shown that healthy subjects do not meet the basic predictions of the task (i.e. prefer options with positive long-
Annette eHorstmann +7 more
doaj +1 more source
Brain Sciences, 2021 Findings on executive functions (EFs) in binge-eating disorder (BED) are inconsistent and possibly biased by associated comorbidities. This study aimed to identify whether distinct levels of physical and mental comorbidity are related to EFs in BED ...
Nele Busch +2 more
doaj +1 more source
Molecular Metabolism, 2017 Objective/methods: DNA methylation plays an important role in obesity and related metabolic complications. We examined genome-wide DNA promoter methylation along with mRNA profiles in paired samples of human subcutaneous adipose tissue (SAT) and omental ...
Maria Keller +21 more
doaj +1 more source
Journal of Eating Disorders, 2023 Background Although avoidant/restrictive food intake disorder (ARFID) presents the replacement and extension of feeding disorders of infancy and childhood, previous research into ARFID concentrated mainly on older patients.
Luise Brosig +6 more
doaj +1 more source
Adipose-specific phospholipase as regulator of adiposity [PDF]
Nutrition Reviews, 2009 A white adipose-tissue-specific intracellular phospholipase, which releases arachidonic acid from position sn-2 of phospholipids, was recently discovered and named AdPLA. When AdPLA was induced by feeding or by insulin treatment, the arachidonic acid released from phospholipids acted as a precursor for the formation of prostaglandin E(2) (PGE(2 ...
openaire +2 more sources
Reliance on model-based and model-free control in obesity
Scientific Reports, 2020 Consuming more energy than is expended may reflect a failure of control over eating behaviour in obesity. Behavioural control arises from a balance between two dissociable strategies of reinforcement learning: model-free and model-based.
Lieneke K. Janssen +4 more
doaj +1 more source
Frontiers in Human Neuroscience, 2015 Previous cross-sectional studies on body-weight-related alterations in brain structure revealed profound changes in the gray matter (GM) and white matter (WM) that resemble findings obtained from individuals with advancing age. This suggests that obesity
Karsten eMueller +13 more
doaj +1 more source
The genetics of adiposity [PDF]
Current Opinion in Genetics & Development, 2018 Genome-wide discovery efforts have identified more than 500 genetic loci associated with adiposity traits. The vast majority of these loci were found through large-scale meta-analyses for body mass index (BMI) and waist-to-hip ratio (WHR), and in European ancestry populations.
openaire +2 more sources
Diabetes Care, 2002 At a symposium titled “Adipose Tissue as a Secretory Organ” at the American Diabetes Association (ADA), San Francisco, June 2002, Jeffrey Flier (Boston, MA) discussed the effects of visceral obesity. While reviewing the differing components of the metabolic syndrome, which to large extent are driven by insulin resistance, he asked, “Where does the ...
openaire +2 more sources
A novel thermoregulatory role for PDE10A in mouse and human adipocytes
EMBO Molecular Medicine, 2016 Phosphodiesterase type 10A (PDE10A) is highly enriched in striatum and is under evaluation as a drug target for several psychiatric/neurodegenerative diseases.
Mohammed K Hankir +17 more
doaj +1 more source