Results 191 to 200 of about 84,802 (258)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Beyond omics: From descriptive profiling to causal and scalable design of fermentation microbiomes

open access: yesiMeta, EarlyView.
Fermentation microbiomes play essential roles in food production, feed preservation, waste valorization, and diverse sustainable industrial processes. Although multi‐omics and systems biology have substantially advanced our understanding of their assembly, interactions, and functional dynamics, industrial translation remains constrained by fragmented ...
Dongze Niu   +22 more
wiley   +1 more source

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Soil‐derived, gut‐dominant generalist bacteria shape the fitness of folivorous larvae

open access: yesiMeta, EarlyView.
Whether Lepidoptera harbor a conserved core gut microbiome has long remained contentious. Through large‐scale microbiome profiling of folivorous larvae, their host plants, and associated soils across three climatically distinct regions of China, we identify two soil‐derived generalist bacteria, Ralstonia insidiosa and Delftia sp., that colonize 97.92 ...
Yu‐xuan Zheng   +11 more
wiley   +1 more source

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae

open access: yesiMeta, EarlyView.
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim   +9 more
wiley   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

open access: yesiNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang   +9 more
wiley   +1 more source

Drought Risk in Mango and Avocado Orchards: Insights Into Plant Water Relations and Irrigation‐Related Agronomic Solutions

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT Climate change is making water availability more uncertain, with growing consequences for the productivity and long‐term sustainability of tropical and subtropical fruit orchards. Mangifera indica L. and Persea americana Mill. both require large amounts of water to sustain growth and productivity.
Eleonora Cataldo
wiley   +1 more source

Evaluating Water–Energy–Food Nexus Strategies to Address Resource Scarcity in the Crocodile River Catchment, South Africa

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT The water–energy–food (WEF) nexus approach highlights the interdependence of water, energy and food resources, all of which play central roles in agriculture, especially irrigation. A WEF nexus lens was applied to Mpumalanga's Crocodile River catchment, a vital irrigation area that significantly contributes to South Africa's staple food ...
N. Masekwana   +3 more
wiley   +1 more source

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