Results 21 to 30 of about 2,955 (229)

Novel regulator of acylated ghrelin, CF801, reduces weight gain, rebound feeding after a fast, and adiposity in mice

Frontiers in Endocrinology, 2015
Ghrelin is a 28 amino-acid hormonal peptide that is intimately related to the regulation of food intake and body weight. Once secreted, ghrelin binds to the growth hormone secretagogue receptor-1a (GHSR-1a), the only known receptor for ghrelin and is ...
Martin K Wellman, Zachary Robert Patterson, Harry eMackay, Joseph E Darling, Bharath K Mani, Jeffrey eZigman, James L Hougland, Alfonso eAbizaid   +7 more
doaj   +2 more sources

Early childhood weight gain and alanine aminotransferase at age 8: an adjunct study of the Japan Environment and Children’s Study [PDF]

BMC Medicine
Background The critical age window during which early-life adiposity impacts liver health remains unclear. This study aimed to identify the timing of adiposity gain associated with elevated alanine aminotransferase (ALT) levels in 8-year-old children ...
Naw Awn J-P, Keiko Yamasaki, Naomi Mitsuda, Masamitsu Eitoku, Ryuhei Nagai, Mariko Araki, Mariko Taniguchi-Ikeda, Narufumi Suganuma   +7 more
doaj   +2 more sources

The 5:2 diet induces male-specific weight loss and sex-independent enhancement of lipid storage in mice via activation of GHSR [PDF]

Frontiers in Nutrition
IntroductionDespite its popularity and reported benefits in humans, preclinical characterization of the broader physiological impact of the 5:2 diet and potential mechanisms of action are lacking.MethodsTo address this deficit, male and female wild-type (
Amanda K. E. Hornsby, Oscar D. T. Powell, Irina A. Guschina, Taylor J. Williams, Katie D. Lines, Luke D. Roberts, Jeffrey S. Davies, Timothy Wells   +7 more
doaj   +2 more sources

Determinants of Adiposity Rebound Timing in Children [PDF]

Journal of Pediatrics, 2017
Edward H Ip, Sarah A Marshall, Joseph A Skelton   +2 more
exaly   +2 more sources

Comparing BMI with skinfolds to estimate age at adiposity rebound and its associations with cardio-metabolic risk markers in adolescence. [PDF]

Int J Obes (Lond), 2019
Background: Body mass index (BMI) reaches a nadir in mid-childhood, known as the adiposity rebound (AR). Earlier AR is associated with a higher risk of cardio-vascular diseases in later life.
Di Gravio C, Krishnaveni GV, Somashekara R, Veena SR, Kumaran K, Krishna M, Karat SC, Fall CHD.   +7 more
europepmc   +2 more sources

Pre-Birth and Early-Life Factors Associated With the Timing of Adiposity Peak and Rebound: A Large Population-Based Longitudinal Study

Frontiers in Pediatrics, 2021
Background: The late occurrence of adiposity peak (AP) and the early occurrence of adiposity rebound (AR) are considered the earliest indicators for obesity and its related health conditions later in life.
Dan Lin, Didi Chen, Didi Chen, Jun Huang, Yun Li, Xiaosa Wen, Xiaosa Wen, Ling Wang, Huijing Shi   +8 more
doaj   +1 more source

Investigation of umbilical cord serum miRNAs associated with childhood obesity: A pilot study from a birth cohort study

Journal of Diabetes Investigation, 2022
We investigated umbilical cord serum microRNA (miRNA) profiles to identify biomarkers of a risk for obesity later in life. Participating children were divided into high‐ and low‐risk groups of obesity based on the timing of adiposity rebound and the body
Rieko Takatani, Yusuke Yoshioka, Tomoko Takahashi, Masahiro Watanabe, Aya Hisada, Midori Yamamoto, Kenichi Sakurai, Tomozumi Takatani, Naoki Shimojo, Hiromichi Hamada, Takahiro Ochiya, Chisato Mori   +11 more
doaj   +1 more source

Premature Birth is an Independent Risk Factor for Early Adiposity Rebound: Longitudinal Analysis of BMI Data from Birth to 7 Years. [PDF]

Nutrients, 2020
Adiposity rebound (AR) refers to the second rise of the body mass index (BMI) curve that usually occurs physiologically between five and seven years of age.
Baldassarre ME, Di Mauro A, Caroli M, Schettini F, Rizzo V, Panza R, De Giorgi A, Capozza M, Fanelli M, Laforgia N.   +9 more
europepmc   +2 more sources

Weight, height and body mass index nomograms; early adiposity rebound in a sample of children in Tehran, Iran

International Journal of Preventive Medicine, 2013
Background: Assessing growth is a useful tool for defining health and nutritional status of children. The objective of this study was to construct growth reference curves of Iranian infants and children (0-6 years old) and compare them with previous and ...
Mostafa Hosseini, Iman Navidi, Bahare Hesamifard, Mahmoud Yousefifard, Nasim Jafari, Sakine Ranji Poorchaloo, Neamatollah Ataei   +6 more
doaj   +1 more source

Sex-specific association between elective cesarean section and growth trajectories in preschool children: A prospective birth cohort study

Frontiers in Public Health, 2022
BackgroundElective cesarean section (ECS) primarily contributes to the rising cesarean section (CS) rate, and much attention has been attracted to its health consequences.
Shanshan Zhang, Jixing Zhou, Mengting Yang, Fu Zhang, Xingyong Tao, Fangbiao Tao, Kun Huang, Kun Huang   +7 more
doaj   +1 more source