Results 41 to 50 of about 2,955 (229)

Earlier and later adiposity rebound according to temperament differences.

, 2018
Vertical axis: AR = adiposity rebound differences scaled in weeks. Positive numbers represent later adiposity rebound (lower obesity risk) for those scoring higher than 2 standard deviations on the temperament dimension.
Eivind Ystrom (4278460), Margarete E. Vollrath (5949932), Sandrine Péneau (474112), Marie Françoise Rolland-Cachera (5949935), Sarah E. Hampson (776277)   +4 more
core   +1 more source

Association of a body mass index genetic risk score with growth throughout childhood and adolescence.

PLoS ONE, 2013
BackgroundWhile the number of established genetic variants associated with adult body mass index (BMI) is growing, the relationships between these variants and growth during childhood are yet to be fully characterised. We examined the association between
Nicole M Warrington, Laura D Howe, Yan Yan Wu, Nicholas J Timpson, Kate Tilling, Craig E Pennell, John Newnham, George Davey-Smith, Lyle J Palmer, Lawrence J Beilin, Stephen J Lye, Debbie A Lawlor, Laurent Briollais   +12 more
doaj   +1 more source

Associations of routine breakfast and napping habits with early adiposity rebound by age 3 years: a population-based cohort study in Japan [PDF]

Clinical and Experimental Pediatrics
Background Early adiposity rebound (AR) is a key predictor of later obesity and metabolic risk, yet modifiable factors related to early AR remain understudied in large populations.
Toshifumi Yodoshi
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

BMI peak in infancy as a predictor for later BMI in the Uppsala Family Study. [PDF]

, 2009
BACKGROUND: The development of obesity through childhood, often characterized by using body mass index (BMI), has received much recent interest because of the rapidly increasing levels of obesity worldwide. However, the extent to which the BMI trajectory
Silverwood, RJ, Leon, DA, T J Cole, D A Leon, R J Silverwood, De Stavola, BL, Cole, TJ, B L De Stavola   +7 more
core   +1 more source

Prevalence of overweight, obesity, and early adiposity rebound in nursery school children in southeastern France

, 2022
International audienceBackgroundThe aim of the present study was to assess the prevalence of overweight, obesity, and early adiposity rebound in nursery school children aged 3.5–4.5 years and to evaluate associations with deprivation.MethodsA cross ...
Bernard, O., Roth, B., Reynaud, R., Gentile, S., Reynaud, Rachel, Pauly, V., Negrec, V.   +6 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Long-term trends in BMI: are contemporary childhood BMI growth references appropriate when looking at historical datasets? [PDF]

, 2009
Background Body mass index (BMI) is the most widely used surrogate measure of adiposity, and BMI z-scores are often calculated when comparing childhood BMI between populations and population sub-groups. Several growth references are currently used as the
De Stavola, Bianca L, Silverwood, RJ, Leon, DA, Leon, David A, de Stavola, BL, Silverwood, Richard   +5 more
core   +1 more source

Transition patterns of weight status: A cohort study of Chinese school-age children

Frontiers in Public Health, 2022
BackgroundChildhood overweight and obesity are increasing public concerns. However, little is known about the transition patterns of childhood weight status, especially in developing countries.
Xin Hu, Xin Hu, Linglin Tan, Zhaoxin Wang, Zhaoxin Wang, Jing Zhang   +5 more
doaj   +1 more source