Results 51 to 60 of about 2,955 (229)

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park, Emily J. Koubek, Richard Beare, Lynn Ang, Brian C. Callaghan, Rodica Pop‐Busui, Eva L. Feldman, Evan L. Reynolds   +7 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Effect of oral glucose administration on rebound growth hormone release in normal and obese women: the role of adiposity, insulin sensitivity and ghrelin. [PDF]

PLoS ONE, 2015
Metabolic substrates and nutritional status play a major role in growth hormone (GH) secretion. Uncovering the mechanisms involved in GH secretion following oral glucose (OG) administration in normal and obese patients is a pending issue.The aim of this ...
Lara Pena-Bello, Sonia Pertega-Diaz, Elena Outeiriño-Blanco, Jesus Garcia-Buela, Sulay Tovar, Susana Sangiao-Alvarellos, Carlos Dieguez, Fernando Cordido   +7 more
doaj   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis

Advanced Materials, EarlyView.
Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena, Lucia Suarez, Aitor Ontoria, Francisca J. Benitez, Elixabete Rezabal, María Soledad Orellano, Marcelo Calderón, Cristián Huck‐Iriart, Agustin S. Picco, Matias L. Picchio, Ana Beloqui   +10 more
wiley   +1 more source

Childhood and Adolescent Obesity: A Review

Frontiers in Pediatrics, 2021
Obesity is a complex condition that interweaves biological, developmental, environmental, behavioral, and genetic factors; it is a significant public health problem.
Alvina R. Kansra, Sinduja Lakkunarajah, M. Susan Jay   +2 more
doaj   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

E. coli Extracellular Matrix: A Tunable Composite With Hierarchical Structure

Advanced Materials, EarlyView.
The complex composite‐like mechanical behavior of E. coli biofilm matrix is the result of a synergic contribution of the rigid curli and swelling pEtN‐cellulose, and emerges from specific ratio and assembly conditions. The interactions between the two fibers govern biofilm hydration and characteristic wrinkling patterns, providing crucial insights for ...
Macarena Siri, Agustín Mangiarotti, Anne Seewald, Nikolai Rosenthal, Shahrouz Amini, Emeline Raguin, Peter Fratzl, Cécile M. Bidan   +7 more
wiley   +1 more source

Adiposity rebound and height velocity in patients with Congenital Adrenal Hyperplasia [PDF]

Objective: Adiposity rebound is the first rise in BMI that occurs after the initial decrease during infancy. Early adiposity rebound, before age 5, is a risk factor for later obesity and metabolic problems.
Chen, Minglu, de Bruin, Christiaan, Neumann, Uta, Lenherr-Taube, Nina, Natarajan, Anuja, Vieites, Ana, Amin, Nadia, Marginean, Otilia, Seneviratne, Sumudu Nimali, Balagamage, Chamila, Bachega, Tânia, Flück, Christa E., Shenoy, Savitha, Iotova, Violeta, Tonge, Joseph, Janus, Dominika, Amr, Nermine H., Krone, Nils, Clemente-León, María, Mazen, Inas, Bryce, Jillian, Poyrazoğlu, Şükran, Stancampiano, Marianna Rita, Tadokoro-Cuccaro, Rieko, Lang, Zi-Qiang, Morris, Cheryl, Yeste, Diego, Schwitzgebel Luscher, Valérie, Fu, Antony, Anverdeen, Fathima A., Rees, D. Aled, Salerno, Mariacarolina, Krone, Ruth, Markosyan, Renata, Thankamony, Ajay, Bonfig, Walter, de Vries, Liat, Globa, Evgenia, Bacila, Irina, Miles, Harriet, Probst-Scheidegger, Ursina, Davies, Justin H., Cools, Martine, Perez, Alegria Ferri, Gazdagh, Gabriella, Russo, Gianni, Randell, Tabitha, El Kaddouri, H., Güven, Ayla, Utari, Agustini, Ortolano, Rita, Banaszak-Ziemska, Magdalena, Tomlinson, Jeremy W., De Sanctis, Luisa, Collins, Gary S.; id_orcid, Mohnike, Klaus L., Dawson, Jeremy, van der Kamp, Hetty J., Niedziela, Marek, Shnorhavorian, Margarett, Ahmed, S. Faisal, Baronio, Federico, Lawrence, Neil R., Elsedfy, Heba, Hannema, Sabine E., Gevers, Evelien, German, Alina, Ali, Salma R., Birkebæk, Niels Holtum, Wasniewska, Malgorzata, de Miranda, Mirela Costa, Alimussina, Malika   +71 more
core   +1 more source

Does the age at adiposity rebound reflect a critical period? [PDF]

, 2019
In 1984, Rolland-Cachera et al. showed that the age at adiposity rebound (AR) was associated with later weight status, whereby an early AR confers greater risk of obesity.
Rolland-Cachera, MF, Rolland-Cachera, Marie-Françoise, Cole, T. J., Cole, TJ   +3 more
core   +1 more source