Results 71 to 80 of about 2,955 (229)

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source

Vztah adiposity rebound k profilu vývoje markerů tělesného složení [PDF]

, 2022
The goal of this diploma thesis is to find out which from the components of body composition clarify adiposity rebound of Body Mass Index (AR BMI). The results were obtained by the visual comparison of the curve profile with the curve profile of the ...
Varhoľáková, Marianna
core  

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Physical fitness in preschool children : correlates and intervention effects [PDF]

, 2011
Summary: Children’s physical fitness has decreased over the last decades. At the same time, the prevalence of overweight and obesity in children has increased dramatically. For public health, these trends are alarming because overweight and a decrease in
Bänteli-Niederer, Iris
core   +1 more source

Body Mass Index Changes at 1.5 and 3 Years of Age Affect Adult Body Composition

Pediatric Reports
Early childhood lays the foundation for many outcomes in later life. Recent studies suggest that early childhood development may contribute to lifestyle-related diseases such as obesity, type 2 diabetes, and cardiovascular disease in adulthood; however ...
Chiharu Miyayama, Hiromichi Shoji, Yayoi Murano, Kanami Ito, Mizue Saita, Toshio Naito, Hiroshi Fukuda, Toshiaki Shimizu   +7 more
doaj   +1 more source

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

Advanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang, Meng‐Hao Li, Liang Cheng, Tian‐Shou Zhang, Hui Hui, Yan Wang, Hong‐Pu Zhang, Bo‐Wen Liu, Lin Wang, Ying‐Wei Yang   +9 more
wiley   +1 more source

Cross-sectional association analysis results for birth measures, BMI and age at adiposity peak (AP) and BMI and age at adiposity rebound (AR) in the ALSPAC and Raine cohorts.

, 2013
Cross-sectional association analysis results for birth measures, BMI and age at adiposity peak (AP) and BMI and age at adiposity rebound (AR) in the ALSPAC and Raine cohorts.
Lawrence J. Beilin (102125), Laurent Briollais (20179), Debbie A. Lawlor (95270), Stephen J. Lye (102140), Craig E. Pennell (102109), Lyle J. Palmer (95287), George Davey-Smith (151784), Nicole M. Warrington (102078), Yan Yan Wu (102096), Nicholas J. Timpson (111625), John Newnham (407632), Laura D. Howe (188892), Kate Tilling (213507)   +12 more
core   +1 more source

Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity

Molecular Metabolism, 2016
Objective: A major challenge for obesity treatment is the maintenance of reduced body weight. Diet-induced obese mice are resistant to achieving normoweight once the obesogenic conditions are reversed, in part because lowered circulating leptin leads to ...
Kavaljit H. Chhabra, Jessica M. Adams, Graham L. Jones, Miho Yamashita, Martin Schlapschy, Arne Skerra, Marcelo Rubinstein, Malcolm J. Low   +7 more
doaj   +1 more source