Results 41 to 50 of about 121,408 (279)

The k-adjacency operators and adjacency Jacobi matrix on distance-regular graphs

open access: yesBoletín de la Sociedad Matemática Mexicana, 2023
We deal in this work with a class of graphs, namely, the class of distance-regular graphs, in which on the basis of $k$-adjacency operators, the adjacency operator $A$ of a distance-regular graph is identified as a Jacobi matrix. To get so, the set of the $k$-adjacency operators is recognized as a canonical basis in a certain Hilbert space, where the ...
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A new matrix representation of multidigraphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2020
In this article, we introduce a new matrix associated with a multidigraph, named as the complex adjacency matrix. We study the spectral properties of bipartite multidigraphs corresponding to the complex adjacency matrix.
Sasmita Barik, Gopinath Sahoo
doaj   +1 more source

Predicting criticality and dynamic range in complex networks: effects of topology

open access: yes, 2010
The collective dynamics of a network of coupled excitable systems in response to an external stimulus depends on the topology of the connections in the network.
Daniel B. Larremore   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Moment-Based Spectral Analysis of Large-Scale Generalized Random Graphs

open access: yesIEEE Access, 2017
This paper investigates the spectra of the adjacency matrix and Laplacian matrix for an artificial complex network model-the generalized random graph. We deduce explicit expressions for the first four asymptotic spectral moments of the adjacency matrix ...
Qun Liu, Zhishan Dong, En Wang
doaj   +1 more source

Contribution of directedness in graph spectra

open access: yesPhysical Review Research, 2022
In graph analyses, directed edges are often approximated to undirected ones so that the adjacency matrices may be symmetric. However, such a simplification has not been thoroughly verified. In this study, we investigate how directedness affects the graph
Masaki Ochi, Tatsuro Kawamoto
doaj   +1 more source

An algebraic analysis of the graph modularity

open access: yes, 2014
One of the most relevant tasks in network analysis is the detection of community structures, or clustering. Most popular techniques for community detection are based on the maximization of a quality function called modularity, which in turn is based upon
Fasino, Dario, Tudisco, Francesco
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

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