Results 61 to 70 of about 30,707 (261)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Minimum eigenvalue of the complement of tricyclic graphs with n-4 pendent vertexes
Journal of Hebei University of Science and Technology, 2019 In order to discuss the minimum eigenvalue of adjacency matrix in the class of complementary graphs of the tricyclic graph with a given order of n and n－4 pendent vertexes, the unique graph whose minimum eigenvalue reaches the minimum is characterized ...
Hongjuan JU, Yingjie LEI
doaj +1 more source
Hierarchical data structures for flowchart
Scientific Reports, 2023 Flowcharts have broad applications in the fields of software development, engineering design, and scientific experimentation. Current flowchart data structure is mainly based on the adjacency list, cross-linked list, and adjacency matrix of the graph ...
Peng Zhang, Wenzhang Dou, Huaping Liu
doaj +1 more source
Matchings on trees and the adjacency matrix: A determinantal viewpoint
Random Structures & Algorithms, 2023 AbstractLet be a finite tree. For any matching of , let be the set of vertices uncovered by . Let be a uniform random maximum size matching of . In this paper, we analyze the structure of . We first show that is a determinantal process. We also show that for most vertices of , the process in a small neighborhood of that vertex can be well ...
openaire +3 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Determinantal properties of Boolean graphs using recursive approach
AKCE International Journal of Graphs and CombinatoricsThe aim of this paper is to study the determinant and inverse of the adjacency matrices of weighted and directed versions of Boolean graphs. Our approach is recursive. We describe the adjacency matrix of a weighted Boolean graph in terms of the adjacency
Gahininath Sonawane +2 more
doaj +1 more source
Reducing Rank of the Adjacency Matrix by Graph Modification
Theoretical Computer Science, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Syed Mohammad Meesum +2 more
openaire +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source