Results 81 to 90 of about 122,412 (281)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Universal Adjacency Matrices with Two Eigenvalues [PDF]

open access: yes
AMS Mathematics Subject Classification: 05C50.Adjacency matrix;Universal adjacency matrix;Laplacian matrix;signless Laplacian;Graph spectra;Eigenvalues;Strongly regular ...
Haemers, W.H., Omidi, G.R.
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Local Out-Tournaments with Upset Tournament Strong Components I: Full and Equal {0,1}-Matrix Ranks [PDF]

open access: yes, 2010
A digraph D is a local out-tournament if the outset of every vertex is a tournament. Here, we use local out-tournaments, whose strong components are upset tournaments, to explore the corresponding ranks of the adjacency matrices.
Derby, Jason M.   +2 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

The adjacency matrix and the discrete Laplacian acting on forms

open access: yes, 2015
We study the relationship between the adjacency matrix and the discrete Laplacian acting on 1-forms. We also prove that if the adjacency matrix is bounded from below it is not necessarily essentially self-adjoint.
Baloudi, Hatem   +2 more
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Adjacency Matrix of Product of Graphs

open access: yesKalpa Publications in Computing, 2018
In graph theory, different types of matrices associated with graph, e.g. Adjacency matrix, Incidence matrix, Laplacian matrix etc. Among all adjacency matrix play an important role in graph theory. Many products of two graphs as well as its generalized form had been studied, e.g., cartesian product, 2−cartesian product, tensor product, 2−tensor product
Urvashi Acharya, Himali Mehta
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A New Perspective on the Average Mixing Matrix

open access: yes, 2017
We consider the continuous-time quantum walk defined on the adjacency matrix of a graph. At each instant, the walk defines a mixing matrix which is doubly-stochastic. The average of the mixing matrices contains relevant information about the quantum walk
Coutinho, Gabriel   +3 more
core  

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