Results 71 to 80 of about 121,408 (279)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Distributed stochastic gradient descent for link prediction in signed social networks
EURASIP Journal on Advances in Signal Processing, 2019 This paper considers the link prediction problem defined over a signed social network, where the relationship between any two network users can be either positive (friends) or negative (foes).
Han Zhang, Gang Wu, Qing Ling
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Cospectral constructions for several graph matrices using cousin vertices
Special Matrices, 2021 Graphs can be associated with a matrix according to some rule and we can find the spectrum of a graph with respect to that matrix. Two graphs are cospectral if they have the same spectrum.
Lorenzen Kate
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Hermitian Adjacency Matrix of Digraphs and Mixed Graphs [PDF]
Journal of Graph Theory, 2016 AbstractThe article gives a thorough introduction to spectra of digraphs via its Hermitian adjacency matrix. This matrix is indexed by the vertices of the digraph, and the entry corresponding to an arc from x to y is equal to the complex unity i (and its symmetric entry is ) if the reverse arc is not present.
Guo, Krystal, Mohar, Bojan
openaire +2 more sources
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Regression and Singular Value Decomposition in Dynamic Graphs
, 2020 Most of real-world graphs are {\em dynamic}, i.e., they change over time. However, while problems such as regression and Singular Value Decomposition (SVD) have been studied for {\em static} graphs, they have not been investigated for {\em dynamic ...
Chehreghani, Mostafa Haghir
core
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Universal Adjacency Matrices with Two Eigenvalues [PDF]
AMS Mathematics Subject Classification: 05C50.Adjacency matrix;Universal adjacency matrix;Laplacian matrix;signless Laplacian;Graph spectra;Eigenvalues;Strongly regular ...
Haemers, W.H., Omidi, G.R.
core +1 more source