Results 121 to 130 of about 32,165 (251)

Does decompression adjacent to arthrodesis in the lumbar spine predispose patients to adjacent segment degeneration and disease: A retrospective analysis. [PDF]

J Orthop, 2023
Paziuk T, Neuman BJ, Conaway W, Kothari P, Henry TW, Kepler CK, Schroeder GD, Vaccaro AR, Hilibrand AS.   +8 more
europepmc   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

The incidence of adjacent segment degeneration and reoperation after anterior stand-alone fusion of the lumbosacral segment - A prospective clinical and radiological long-term investigation -

Brain and Spine, 2021
Katrin Stosch-Wiechert, Karin Wuertz-Kozak, Alexander Krenauer, Christoph J. Siepe   +3 more
doaj   +1 more source

Biomechanical evaluation of the hybrid pedicle screw-cortical bone trajectory technique in transforaminal lumbar interbody fusion to adjacent segment degeneration-finite element analysis. [PDF]

BMC Musculoskelet Disord, 2023
Zhang R, Kahaer A, Niu H, Wang J, Jumahan A, Qiu Y, Rexiti P, Guo H.   +7 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Adjacent segment degeneration after superior facet joint violation of the lumbar spine. [PDF]

N Am Spine Soc J
McNamee C, Magee B, Storey RN, McDonnell JM, Darwish S, Butler JS.   +5 more
europepmc   +1 more source

Correction: Biomechanical evaluation of the hybrid pedicle screw-cortical bone trajectory technique in transforaminal lumbar interbody fusion to adjacent segment degeneration-finite element analysis. [PDF]

BMC Musculoskelet Disord, 2023
Zhang R, Kahaer A, Niu H, Wang J, Jumahan A, Qiu Y, Rexiti P, Guo H.   +7 more
europepmc   +1 more source

CNTN2 Deficiency Disrupts Ascending Auditory Neuroglial Interactions and Redox Homeostasis in Neural Presbycusis

Advanced Science, EarlyView.
. ABSTRACT Neural presbycusis disrupts auditory timing and speech perception, yet its molecular basis remains poorly understood. This study identifies Cntn2 as the Ranvier's nodal molecule significantly downregulated in aged auditory nerves. Cntn2 heterozygous knockout (Cntn2+/−) mice showed elevated auditory brainstem response thresholds and prolonged
Penghui Chen, Jingyi Zhu, Sihan Huang, Beibei Xu, Maoli Duan, Jingrong Lv, Jiarui Chen, Jun Yang, Shule Hou   +8 more
wiley   +1 more source

Development and internal validation of a clinico-radiological classification system for lumbar adjacent segment degeneration after TLIF. [PDF]

N Am Spine Soc J
Kumar G, Tandon V, Mahajan R, Das K, Nanda A, Mohapatra B, Sangondimath G, Rustagi T.   +7 more
europepmc   +1 more source

The Standing and Sitting Spino-Pelvic Sagittal Alignment in Patients with Instrumented Lumbar Fusion Might Correlate with Adjacent Segment Degeneration. [PDF]

Orthop Surg, 2022
Zhou S, Zhong W, Sun Z, Guo Y, Zhao Y, Li W, Li W.   +6 more
europepmc   +1 more source