Results 81 to 90 of about 249,494 (321)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
When are adjectives raisers? Tough to get it
Bucharest Working Papers in Linguistics, 2007 This article deals with some unsolved problems raised by tough-adjectives in Romance languages. We present some new data from some Romance languages (Romanian, French, Italian) supporting a raising analysis, and we argue that in these languages, unlike ...
Ion Giurgea, Elena Soare
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Using fuzzy logic to handle the semantic descriptions of music in a content-based retrieval system [PDF]
, 2006 This paper explores the potential use of fuzzy logic for semantic music recommendation. We show that a set of affective/emotive, structural and kinaesthetic descriptors can be used to formulate a query which allows the retrieval of intended music.
Leman, Marc, Lesaffre, Micheline
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Semantics of the Adjectives’ Coloratives in the Fiction Prose by A.I. Kuprin and A.S. Serafimovich
Vestnik Volgogradskogo Gosudarstvennogo Universiteta. Seriâ 2. Âzykoznanie, 2016 The article deals with the question of peculiarities of color adjectives' usage in the prose pieces of writers-realists A.I. Kuprin and A.S. Serafimovich of 19th and 20th centuries.
Kamilya Eduardovna Sadrieva
doaj +1 more source
Word order in the Old Italian DP [PDF]
, 2015 In this article I examine the impact of a cartographic approach on research about diachronic change and investigate the internal structure of the DP in Old Italian (OI).
Poletto, Cecilia
core
Nomino-Adjectival Collocation in Written Production of L2 French
, 2021 Vitalija Kazlauskienė
openalex +2 more sources