Results 121 to 130 of about 218,273 (293)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Word sense disambiguation criteria: a systematic study
, 2004 This article describes the results of a systematic in-depth study of the criteria used for word sense disambiguation. Our study is based on 60 target words: 20 nouns, 20 adjectives and 20 verbs.
Audibert, Laurent
core +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
On the Derivation of Denominal Adjectives in Polish
Studies in Polish LinguisticsThis research investigates the derivation of denominal qualitative adjectives in Polish formed by the suffixes ‑liwy, ‑ny, ‑sty, and ‑owy (e.g.
Sebastian Wasak
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
CausaLM: Causal Model Explanation Through Counterfactual Language Models
, 2020 Understanding predictions made by deep neural networks is notoriously difficult, but also crucial to their dissemination. As all ML-based methods, they are as good as their training data, and can also capture unwanted biases.
Feder, Amir +3 more
core
Grammatical Relations and Grammatical Categories in Malay; the Indonesian Prefix MeN- Revisited [PDF]
, 2015 The lexical roots of Malay are flexible with regard to their grammatical categories, which presents a problem in providing grammatical evidence for their category determination.
Tjia, J. (Johnny)
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On the morpho-syntactic properties of relational adjectives in romanian and spanish
Bucharest Working Papers in Linguistics, 2010 This paper analyzes the morpho-syntactic structure of a subclass of Relational adjectives, Th(ematic) adjectives within the framework of Distributed Morphology (Halle and Marantz 1993). Building on Bosque and Picallo’s (1996) classification of Relational
Mihaela Marchis
doaj