Results 91 to 100 of about 789 (269)

On lax transformations, adjunctions, and monads in (∞,2)-categories

open access: yes, 2021
We use the basic expected properties of the Gray tensor product of (∞, 2)-categories to study (co)lax natural transformations. Using results of Riehl–Verity and Zaganidis we identify lax transformations between adjunctions and monads with commutative ...
Haugseng, Rune
core  

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

open access: yesAdvanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang   +11 more
wiley   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

open access: yesAdvanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu   +9 more
wiley   +1 more source

Coalgebraic semantics for timed processes

open access: yes, 2006
We give a coalgebraic formulation of timed processes and their operational semantics. We model time by a monoid called a “time domain”, and we model processes by “timed transition systems”, which amount to partial monoid actions of the time domain or ...
Simpson, Alexander   +6 more
core   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

open access: yesAdvanced Science, EarlyView.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang   +9 more
wiley   +1 more source

PancDS in Real‐World Practice: A Prospective Multicenter Validation of a Clinical Decision‐Support System Bridging Experience Gaps in Pancreatic Lesion Diagnosis

open access: yesAdvanced Science, EarlyView.
A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang   +13 more
wiley   +1 more source

Preprint Number 15–49 GENERATING SUBLOCALES BY SUBSETS AND RELATIONS: A TANGLE OF ADJUNCTIONS

open access: yes, 2016
: Generalizing the obvious representation of a subspace Y ⊆ X as a sublocale in Ω(X) by the congruence {(U, V) | U ∩ Y = V ∩ Y} one obtains the congruence {(a, b) | o(a)∩S = o(b)∩S}, first with sublocales S of a frame L, which (as it is well known ...
Picado, Jorge   +5 more
core   +1 more source

Quillen adjunctions induce adjunctions of quasicategories

open access: yes, 2015
We prove that a Quillen adjunction of model categories (of which we do not require functorial factorizations and of which we only require finite bicompleteness) induces a canonical adjunction of underlying quasicategories.
openaire   +3 more sources

Dynamic Evolution‐Controlled Parabolic‐Shaped Microstructures for Ultra‐Black Surface via Self‐Assembled Microsphere Mask Etching

open access: yesAdvanced Science, EarlyView.
A robust, substrate‐independent fabrication approach overcomes the spectral and geometric limitations of traditional stray‐light suppression. By combining ink spray‐coating with self‐assembled microsphere mask etching, this method produces parabolic‐shaped microstructures on diverse planar and curved engineering components.
Yiming Li   +5 more
wiley   +1 more source

Intrinsic Mechanical Parameters and their Characterization in Solid‐State Lithium Batteries

open access: yesAdvanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
This review focuses on the intrinsic mechanical parameters and their associated characterization in solid‐state batteries. The physical significance of mechanics parameters is introduced with exhaustive classifications by elastic, plastic deformations and fracture in bulk, adhesion, friction at interfaces, and mechanical fatigue in cells ...
Shuai Hao   +5 more
wiley   +1 more source

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