Results 51 to 60 of about 1,585,740 (230)

[Adjustment disorder and DSM-5: A review].

, 2016
This paper exposes the complexity and discrete characteristic of the adjustment disorder with reference to its clinical and scientific diagnosis. Even though the disorder occurs in frequent clinical circumstances after important life events, such as ...
Appart, A, Bihain, F, Lange, A-K, Sievert, I, Tordeurs, David   +4 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The relationship between negative emotions and adjustment disorder in young adults: the mediating role of rumination and insomnia

Frontiers in Psychiatry
IntroductionThis study aimed to investigate the influence of negative emotions on adjustment disorder (AjD) in young adults, focusing on the mediating role of rumination and insomnia.MethodsThe study recruited 2015 young patients (aged 18–35) receiving ...
Xinyue Shao, Zhao Dong, Shuai Zhang, Yunyun Qiao, Hongwei Zhang, Hua Guo   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Managing the dual challenge: Mood disorders in a patient with multidrug-resistant tuberculosis

BLDE University Journal of Health Sciences
Multidrug-resistant tuberculosis (MDR-TB) is defined as resistance to isoniazid and rifampicin, with or without resistance to other anti-TB drugs. Drug-resistant TB requires a long course of treatment with multiple drugs depending on drug sensitivity ...
S. Shyam, Keertivardhan D. Kulkarni, Saurav Suresh   +2 more
doaj   +1 more source

Suicidal behavior in adjustment disorder patients [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2011
Objective: As with many psychiatric disorders, also suicide and suicide attempts are the major causes of mortality and morbidity in patients with adjustment disorder.
Barbaros Ozdemir, Mehmet Ak, Ali Doruk, Abdullah Bolu, Fuat Ozgen   +4 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Assessing stressor exposure, chemsex use, and adjustment disorder in a sample of men who have sex with men

European Journal of Psychotraumatology
Background: Evidence suggests that men who have sex with men (MSM) experience heightened risk for stressor-related mental health issues. This may be exacerbated among those who engage in chemsex; recreational substance use during sex. Valid assessment of
Martin Robinson, Yafit Levin, Rahel Bachem, Nadia Badran, Kostas Papageorgiou, Emanuele Fino   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source