Results 101 to 110 of about 152,778 (309)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
DESIGN-STAGE ADJUSTMENT OF ROTOR CRITICAL SPEEDS
Advanced Engineering Research, 2011 Know-how and the computer-applied diversity algorithm (removal) for the operational and critical rotation speeds of the rotor at the design stage (critical frequencies adjustment) are offered.
Oleg O. Polushkin, Oleg A. Polushkin
doaj
LABOR ADJUSTMENT DYNAMICS: AN APPLICATION OF SYSTEM GMM [PDF]
This paper analyzes the dynamics of the Portuguese labor market using micro data: implications of adjustment costs to input factor adjustment throughout the business cycle are discussed; the current situation of the Portuguese labor market is reviewed ...
Pedro M. Esperança
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Delay Adjustment Method at Transfer Station of High-Speed Railway
Advances in Mechanical Engineering, 2013 Passenger transfer is one of the important research contents after the network operation of high-speed railway. Due to the high operation speed and high frequency, delays at transfer stations may occur frequently, leading to some potential safety ...
Li Xiaojuan, Han Baoming, Zhang Qi
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Optimal Adjustment Paths in a Monetary Union. CEPS Working Document No. 424 / July 2016 [PDF]
, 2016 Adjustment to an external imbalance is more difficult within a monetary union if wages are sticky. Periods of high unemployment are usually necessary to achieve the required real depreciation (internal devaluation).
Gros, Daniel., Belke, Ansgar
core
Scale economies with regard to price adjustment costs and the speed of price adjustment in Australian manufacturing [PDF]
This paper aims to examine the impact of firm size, industry concentration and the length of production on industry speed of price adjustment. To motivate the paper, an industry pricing model in error correction form is derived from firm pricing ...
Michael Olive
core +1 more source