Results 111 to 120 of about 152,778 (309)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

How do the capital structure and adjustment speed of Islamic banks differ from those of conventional banks? Evidence from the GCC region

open access: yesHumanities & Social Sciences Communications
This study investigates the leverage ratios and speed of adjustment of Islamic and conventional banks over the years 2011–2022. The study focuses on the GCC markets, where most Islamic banks’ assets are located, accounting for 60% of the global Islamic ...
Mohammad Alsharif, Faisal Alnori
doaj   +1 more source

Estimating Single Layer Bi-Channel Neural Networks Architecture for Speed Control of Variable Reluctance Motors

open access: yesEnergies
This study explores the speed adjustment characteristics of the adaptive control of estimated single-layer Bi-channel neural networks (NNs) for Variable Reluctance Motor (VRM) drives.
Hamad Alharkan
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DYNAMIC ADJUSTMENT IN DEMAND EQUATIONS

open access: yes
The focus of this paper is the dynamic adjustment of demand. It is shown that a dynamic specification of the demand equation provides information on: (i) the level of response to a price or expenditure change taking place instantaneously, (ii) how much ...
Asche, Frank
core  

Learning by Investing, Embodiment, and Speed of Convergence [PDF]

open access: yes
This paper sets up a dynamic general equilibrium model to study how the composition of technical progress affects the asymptotic speed of convergence. The following questions are addressed: Will endogenizing a fraction of the productivity increases as ...
Ronald Wendner, Christian Groth
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Speed of adjustment within currency markets

open access: yes, 2006
Speed of adjustment within currency ...
Terry Boulter (13051251)
core  

Asymmetric and time-varying error-correction: an application to labour demand in the UK [PDF]

open access: yes, 1993
In this paper we compare the asymmetric and time-varying error-correction models that have recently been proposed, and apply these to the case of UK aggregate labour demand. The aim of the paper is to investigate the possible co-existence of time-varying
Burgess, Simon M.   +2 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy