Annals of Clinical and Translational Neurology, EarlyView.Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal +11 more
wiley +1 more source
Innovative Mucosal Vaccine Formulations Against Influenza A Virus Infections
Frontiers in Immunology, 2019 Despite efforts made to develop efficient preventive strategies, infections with influenza A viruses (IAV) continue to cause serious clinical and economic problems.
Cynthia Calzas, Christophe Chevalier
doaj +1 more source
Neurologic Manifestations in Laboratory Animals Produced by Organ (Adjuvant) Emulsions [PDF]
, 1947 Lenore M. Kopeloff, Nicholas Kopeloff
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective A substantial part of central nervous system (CNS) disorders remains unexplained, despite various new and minimally invasive diagnostic techniques. Within this rapidly developing diagnostic field, the precise role of brain biopsy is unknown.
Robin W. van Steenhoven +14 more
wiley +1 more source
The Effectiveness of Tuberculo-Glycolipid as an Adjuvant in Eliciting Allergic Encephalomyelitis and Aspermatogenesis [PDF]
, 1959 Jules Freund +2 more
openalex +1 more source
Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan +6 more
wiley +1 more source
A Large Language Model Pipeline for Breast Cancer Oncology [PDF]
arXivLarge language models (LLMs) have demonstrated potential in the innovation of many disciplines. However, how they can best be developed for oncology remains underdeveloped. State-of-the-art OpenAI models were fine-tuned on a clinical dataset and clinical guidelines text corpus for two important cancer treatment factors, adjuvant radiation therapy and ...
arxiv
No evidence of histology subtype-specific prognostic signatures among lung adenocarcinoma and squamous cell carcinoma patients at early stages [PDF]
arXiv, 2014 Background Non-small cell lung cancer (NSCLC) is the predominant histological type of lung cancer, accounting for up to 85% of cases. Disease stage is commonly used to determine adjuvant treatment eligibility of NSCLC patients, however, it is an imprecise predictor of the prognosis of an individual patient.
arxiv
Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling +6 more
wiley +1 more source
Guiding Treatment Strategies: The Role of Adjuvant Anti-Her2 Neu Therapy and Skin/Nipple Involvement in Local Recurrence-Free Survival in Breast Cancer Patients [PDF]
arXivThis study explores how causal inference models, specifically the Linear Non-Gaussian Acyclic Model (LiNGAM), can extract causal relationships between demographic factors, treatments, conditions, and outcomes from observational patient data, enabling insights beyond correlation.
arxiv