Near-infrared laser adjuvant for influenza vaccine. [PDF]
PLoS ONE, 2013 Safe and effective immunologic adjuvants are often essential for vaccines. However, the choice of adjuvant for licensed vaccines is limited, especially for those that are administered intradermally.
Satoshi Kashiwagi +21 more
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Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis [PDF]
Journal of Translational Medicine, 2010 Background Melanoma vaccines have not been optimized. Adjuvants are added to activate dendritic cells (DCs) and to induce a favourable immunologic milieu, however, little is known about their cellular and molecular effects in human skin.
Schaefer Jochen T +6 more
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A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo [PDF]
Frontiers in Immunology, 2018 Dendritic cell activation of CD4 T cells in the lymph node draining a site of infection or vaccination is widely considered the central event in initiating adaptive immunity.
Hannah E. Scales +10 more
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Evaluation of Antibodies Induced by Melanoma Helper Peptide Vaccine and Their Modulation by Vaccine Adjuvants [PDF]
VaccinesBackground/Objectives: Vaccines targeting melanoma antigens can elicit CD8+ T cell responses, but a growing body of work suggests CD4+ T cells also play a role in tumor control.
Emily G. Ashkani +4 more
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Establishing the pig as a large animal model for vaccine development against human cancer [PDF]
Frontiers in Genetics, 2015 Immunotherapy has increased overall survival of metastatic cancer patients, and cancer antigens are promising vaccine targets. To fulfill the promise, appropriate tailoring of the vaccine formulations to mount in vivo cytotoxic T cell (CTL) responses ...
Nana Haahr Overgaard +8 more
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Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) After Polypropylene Mesh Implantation – Protocol of a Pilot Study for Diagnostics and Treatment [PDF]
Journal of Abdominal Wall SurgeryBackgroundAn increasingly vocal movement of patients with systemic complaints, supposedly linked to polypropylene mesh implants, is leading to increasing numbers of patient-preferred mesh-less surgical repairs for inguinal hernia, stress urinary ...
M. J. C. A. M. Gielen +23 more
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Continuous Treatment with IncobotulinumtoxinA Despite Presence of BoNT/A Neutralizing Antibodies: Immunological Hypothesis and a Case Report [PDF]
ToxinsBotulinum Neurotoxin A (BoNT/A) is a bacterial protein that has proven to be a valuable pharmaceutical in therapeutic indications and aesthetic medicine.
Michael Uwe Martin +2 more
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ASIA and BIA-ALCL as adverse reactions to silicone breast implants [PDF]
Revista Brasileira de Cirurgia Plástica, 2023 Adjuvant-induced autoimmune/inflammatory syndrome leads to capsular contracture and fibrosis from the oxidation that takes place in silicone.
Natalia Silva Zahdi +3 more
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Adjuvant-induced autoimmune syndrome triggered by silicone breast implants: systematic review [PDF]
Revista Brasileira de Cirurgia Plástica, 2022 Adjuvant-induced autoimmune syndrome (ASIA) and its diagnostic criteria were described by Shoenfeld in 2011, relating symptoms of autoimmunity to adjuvants, such as silicone, present in breast implants.
Caio Munaretto Giacomazzo +5 more
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Vaccination for Respiratory Syncytial Virus: A Narrative Review and Primer for Clinicians
Vaccines, 2023 Respiratory syncytial virus (RSV) poses a significant burden on public health, causing lower respiratory tract infections in infants, young children, older adults, and immunocompromised individuals.
Kay Choong See
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