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The recent advances in vaccine adjuvants [PDF]

open access: yesFrontiers in Immunology
Vaccine adjuvants, as key components in enhancing vaccine immunogenicity, play a vital role in modern vaccinology. This review systematically examines the historical evolution and mechanisms of vaccine adjuvants, with particular emphasis on innovative ...
Jiayin Xing   +6 more
doaj   +3 more sources

The Effects of Adjuvants on the Wetting and Deposition of Insecticide Solutions on Hydrophobic Wheat Leaves

open access: yesAgronomy, 2022
Pesticide droplet deposition determines the efficacy of pesticide solution and is a critical process in pesticide application. Adding spray adjuvants can improve droplet deposition to a certain extent, but there are currently many types of adjuvants with
Yuying Song   +7 more
doaj   +1 more source

Antigen-Dependent Adjuvanticity of Poly(lactic-co-glycolic acid)-polyethylene Glycol 25% Nanoparticles for Enhanced Vaccine Efficacy

open access: yesVaccines
Background: A key component in modern vaccine development is the adjuvant, which enhances and/or modulates the antigen-specific immune response. In recent years, nanoparticle (NP)-based adjuvants have attracted much research attention owing to their ...
Minxuan Cui   +8 more
doaj   +1 more source

Comparative Immunogenicity Evaluation of Characterized Chitosan-Based and Other Adjuvants for Inactivated Influenza Vaccines

open access: yesЭпидемиология и вакцинопрофилактика, 2016
Chitosan-based adjuvants combine effectiveness, safety and economic feasibility and thus are quite promising for enhancement of influenza control via vaccination, however, problems of characterization and reproducibility remain unresolved; data on ...
L. M. Khantimirova   +3 more
doaj   +1 more source

General characteristics of adjuvants and their mechanisms of action (part 2)

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2021
One of the major public health challenges today is development of new vaccines and technologies to optimize the vaccination process. There is a growing scientific interest in vaccine adjuvants that enhance vaccine immunogenicity.
N. А. Alpatova   +5 more
doaj   +1 more source

Exploration of Pattern Recognition Receptor Agonists as Candidate Adjuvants

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Adjuvants are used to maximize the potency of vaccines by enhancing immune reactions. Components of adjuvants include pathogen-associated molecular patterns (PAMPs) and damage-associate molecular patterns (DAMPs) that are agonists for innate immune ...
Guang Han Ong   +3 more
doaj   +1 more source

A living therapeutic platform for localized in situ modulation of macrophage pyroptosis ameliorates GVHD while preserving GVL

open access: yesJournal of Nanobiotechnology
Background Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation, with the gastrointestinal tract being a primary target organ.
Zhuo Wan   +12 more
doaj   +1 more source

Bacterial-Derived Outer Membrane Vesicles are Potent Adjuvants that Drive Humoral and Cellular Immune Responses

open access: yesPharmaceutics, 2021
Discovery and development of novel adjuvants that can improve existing or next generation vaccine platforms have received considerable interest in recent years.
J. Timothy Prior   +5 more
doaj   +1 more source

Carbohydrate-Based Adjuvants for Vaccine Production

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
Addition of adjuvants is a generally recognized method of enhancing the immunogenicity of vaccines. There is a large variety of  adjuvants, therefore the choice of an adjuvant is based on the  comparison of adjuvants efficacy in animal models, as well as 
S. S. Kurashova   +6 more
doaj   +1 more source

Density and surface tension of aqueous solutions of adjuvants used for tank-mixes with pesticides

open access: yesPlant, Soil and Environment, 2012
Adjuvants are surface active agents that are added to pesticide formulations or tank-mix to facilitate the mixing, application, or efficacy of these products. Addition of adjuvants changes the physico-chemical properties of spray liquid. In this work, we
J. Janků   +4 more
doaj   +1 more source

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