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Vaccine adjuvants: mechanisms and platforms

open access: yesSignal Transduction and Targeted Therapy, 2023
Adjuvants are indispensable components of vaccines. Despite being widely used in vaccines, their action mechanisms are not yet clear. With a greater understanding of the mechanisms by which the innate immune response controls the antigen-specific ...
tingmei zhao, Xiao-he Tian, Jiang yu jie
exaly   +2 more sources

Vaccine Adjuvants: Selection Criteria, Mechanism of Action Associated with Immune Responses and Future Directions [PDF]

open access: yesIranian Journal of Immunology, 2023
The most effective method to minimize the prevalence of infectious diseases is vaccination. Vaccines enhance immunity and provide protection against different kinds of infections.
Arslan Habib   +10 more
doaj   +1 more source

Research Progress of Aluminum Phosphate Adjuvants and Their Action Mechanisms

open access: yesPharmaceutics, 2023
Although hundreds of different adjuvants have been tried, aluminum-containing adjuvants are by far the most widely used currently. It is worth mentioning that although aluminum-containing adjuvants have been commonly applied in vaccine production, their ...
Ting Zhang   +5 more
doaj   +1 more source

Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity

open access: yesVaccines, 2021
Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li   +3 more
doaj   +1 more source

Current status and prospect for development of COVID-19 vaccine adjuvants

open access: yes陆军军医大学学报, 2022
Vaccines are the most economical and effective means to protect against SARS-CoV-2 infection. Adjuvants are able to enhance antigen-specific immune responses, reduce antigen doses and vaccination times, and reshape adaptive immune responses, which are ...
LI Haibo, CHENG Hao
doaj   +1 more source

Research progress in the development of natural-product-based mucosal vaccine adjuvants

open access: yesFrontiers in Immunology, 2023
Mucosal vaccines have great potential and advantages in preventing infection caused by multiple pathogens. In developing mucosal vaccines, the biggest challenge comes from finding safe and effective adjuvants and drug delivery systems. Great progress has
Yingying Gao, Ying Guo
doaj   +1 more source

Towards Sustainable Green Adjuvants for Microbial Pesticides: Recent Progress, Upcoming Challenges, and Future Perspectives

open access: yesMicroorganisms, 2023
Microbial pesticides can be significantly improved by adjuvants. At present, microbial pesticide formulations are mainly wettable powders and suspension concentrations, which are usually produced with adjuvants such as surfactants, carriers, protective ...
Fuyong Lin   +7 more
doaj   +1 more source

Antibiotic adjuvants: synergistic tool to combat multi-drug resistant pathogens

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The rise of multi-drug resistant (MDR) pathogens poses a significant challenge to the field of infectious disease treatment. To overcome this problem, novel strategies are being explored to enhance the effectiveness of antibiotics.
Vikram Kumar   +10 more
doaj   +1 more source

Overview of vaccine adjuvants

open access: yesMedicine in Drug Discovery, 2021
Adjuvants are essential components of vaccines that have been particularly effective at promoting protective humoral immunity to infectious diseases and preventing mortality and morbidity.
Zhenchuan Wu, Keqin Liu
doaj   +1 more source

New-age vaccine adjuvants, their development, and future perspective

open access: yesFrontiers in Immunology, 2023
In the present scenario, immunization is of utmost importance as it keeps us safe and protects us from infectious agents. Despite the great success in the field of vaccinology, there is a need to not only develop safe and ideal vaccines to fight deadly ...
Shailendra Kumar Verma   +6 more
doaj   +1 more source

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