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Vaccine adjuvants: mechanisms and platforms
Signal Transduction and Targeted Therapy, 2023 Adjuvants are indispensable components of vaccines. Despite being widely used in vaccines, their action mechanisms are not yet clear. With a greater understanding of the mechanisms by which the innate immune response controls the antigen-specific ...
Tingmei Zhao +6 more
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Vaccine Potentiation by Combination Adjuvants
Vaccines, 2014 Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by modulating, enhancing, or extending the immune response and at the same time reducing the amount of antigen needed. In contrast to previously licensed adjuvants,
Benoît Levast +5 more
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Current HIV Research, 2010 The vast majority of pathogens invade the body through or establish infections in the mucosal tissues. Development of vaccines to combat mucosal infections represents a top priority. Mucosal immunization has recently attracted much interest as a means of generating protective immunity against mucosal pathogens.
HARANDI A. M., MEDAGLINI D.
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Research progress on emulsion vaccine adjuvants
HeliyonVaccination is the most cost-effective method for preventing various infectious diseases. Compared with conventional vaccines, new-generation vaccines, especially recombinant protein or synthetic peptide vaccines, are safer but less immunogenic than ...
Zhuanqing Huang +5 more
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Adjuvants : an essential component of neisseria vaccines [PDF]
, 2009 Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R. +8 more
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New-age vaccine adjuvants, their development, and future perspective
Frontiers in Immunology, 2023 In the present scenario, immunization is of utmost importance as it keeps us safe and protects us from infectious agents. Despite the great success in the field of vaccinology, there is a need to not only develop safe and ideal vaccines to fight deadly ...
Shailendra Kumar Verma +6 more
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The Epidermis as an Adjuvant [PDF]
Journal of Investigative Dermatology, 2012 It is now clear that the epidermis has an active role in local immune responses in the skin. Keratinocytes are involved early in inflammation by providing first-line innate mechanisms and, in addition, can contribute to adaptive immune responses that may be associated with clinical disease.
Gutowska-Owsiak, D, Ogg, G
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Deutsches Ärzteblatt international, 2011 No abstract available.
Rudert, Maximilian +2 more
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Immune mechanisms of protection: can adjuvants rise to the challenge? [PDF]
, 2010 For many diseases vaccines are lacking or only partly effective. Research on protective immunity and adjuvants that generate vigorous immune responses may help generate effective vaccines against such ...
MacLeod Megan KL +11 more
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Journal of Fungi, 2019 Clonostachys rosea strain ACM941 is an effective biocontrol agent against several crop diseases including Fusarium head blight. In anticipation of its increased relevance going forward, the development of a reliable DNA-based molecular marker to track it
Zerihun A. Demissie +2 more
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