Results 31 to 40 of about 69,334 (300)

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

, 2016
<p><b>INTRODUCTION: </b>Pathogen recognition receptors (PRRs) recognize pathogen-associated molecular patterns, triggering the induction of inflammatory innate responses and contributing to the development of specific adaptive immune ...
K. Huygen, Marta Romano, Kris Huygen, H. Tima Giresse, M. Romano, Hermann Giresse Tima   +5 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Seasonal Influenza Split Vaccines Confer Partial Cross-Protection against Heterologous Influenza Virus in Ferrets When Combined with the CAF01 Adjuvant

Frontiers in Immunology, 2018
Influenza epidemics occur annually, and estimated 5–10% of the adult population and 20–30% of children will become ill from influenza infection. Seasonal vaccines primarily work through the induction of neutralizing antibodies against the principal ...
Dennis Christensen, Jan P. Christensen, Karen S. Korsholm, Louise K. Isling, Karin Erneholm, Allan R. Thomsen, Peter Andersen   +6 more
doaj   +1 more source

Tumor-specific antigens and immunologic adjuvants in cancer immunotherapy.

, 2011
T cell-based cancer immunotherapy relies on advancements made over the last 20 years on the molecular mechanisms underlying the antigenicity of tumors. This review focuses on human tumor antigens recognized by T lymphocytes, particularly the reasons why ...
Coulie, Pierre, Pierre G. Coulie, Francis Brasseur, Teofila Seremet, Seremet, Teofila, Brasseur, Francis   +5 more
core   +1 more source

Protective antiviral immune responses to pseudorabies virus induced by DNA vaccination using dimethyldioctadecylammonium bromide as an adjuvant [PDF]

, 2002
To enhance the efficacy of a DNA vaccine against pseudorabies virus (PRV), we evaluated the adjuvant properties of plasmids coding for gamma interferon or interleukin-12, of CpG immunostimulatory motifs, and of the conventional adjuvants ...
Eddie G. te Lintelo, te Lintelo, E.G., Wim J. A. Boersma, Rooij, E.M.A., van, Yolanda E. de Visser, Boersma, WJA, Lintelo, E.G., te, Boersma, W.J.A., Visser, Y.E., de, Hilgers, LAT, Haagmans, Bart, van Rooij, EMA, Bart L. Haagmans, Bianchi, ATJ, Harrie L. Glansbeek, Hilgers, L.A.T., Haagmans, B.L., Glansbeek, H.L., Andre T. J. Bianchi, van Rooij, E.M.A., Glansbeek, HL, Eugene M. A. van Rooij, de Visser, Y.E., Luuk A. T. Hilgers, Bianchi, A.T.J., Lintelo, EG, de Visser, YE   +26 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Treatment of common warts with the immune stimulant Propionium bacterium parvum Tratamento das verrugas vulgares com o imunoestimulante Propionium bacterium parvum

Anais Brasileiros de Dermatologia, 2012
BACKGROUND: Warts are epithelial proliferations in the skin and mucous membrane caused by various types of HPV. They can decrease spontaneously or increase in size and number according to the patient's immune status.
Nilton Nasser
doaj   +1 more source

Immunological adjuvants in allergy vaccines: Past, present future [PDF]

, 2001
Hundreds of compounds have been tested over the years in a search for adjuvants to incorporate with antigens or allergens to enhance the immune response.
Wheeler, Alan W., Woroniecki, Stefan R.
core   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source