Results 11 to 20 of about 21,995 (302)

Application of built-in adjuvants for epitope-based vaccines [PDF]

PeerJ, 2019
Several studies have shown that epitope vaccines exhibit substantial advantages over conventional vaccines. However, epitope vaccines are associated with limited immunity, which can be overcome by conjugating antigenic epitopes with built-in adjuvants (e.
Yao Lei, Furong Zhao, Junjun Shao, Yangfan Li, Shifang Li, Huiyun Chang, Yongguang Zhang   +6 more
doaj   +2 more sources

Liposomes as Immunological Adjuvants [PDF]

Nature, 1974
ADJUVANTS are widely used to increase antibody formation in experimental animals, for example, Freund's incomplete adjuvant, a water-in-oil emulsion containing the antigen, and Freund's complete adjuvant, which is the same but with killed tubercle bacilli.
Allison, A C, Gregoriadis, G
openaire   +3 more sources

Immune Adjuvant Therapy With Interleukin-7 in a Lymphopenic Patient With Aplastic Anemia and Mucormycosis

Critical Care Explorations, 2023
BACKGROUND:. We report the case of a patient with aplastic anemia and pancytopenia on immune-suppressive therapy who developed invasive pulmonary infection with mucormycosis and was treated with immune adjuvant therapy. CASE SUMMARY:. Given the patient’s
Zachary D. Crees, MD, Dilan A. Patel, MD, Alexandra Dram, BS, Miriam Kim, MD, Michael D. Bern, MD, PhD, Allison R. Eberly, PhD, Kristan Augustin, PharmD, Richard S. Hotchkiss, MD, John F. DiPersio, MD, PhD   +8 more
doaj   +1 more source

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination

Scientific Reports, 2022
Infection is the most common cause of mortality early in life, yet the broad potential of immunization is not fully realized in this vulnerable population. Most vaccines are administered during infancy and childhood, but in some cases the full benefit of
David J. Dowling, Soumik Barman, Alyson J. Smith, Francesco Borriello, Danielle Chaney, Spencer E. Brightman, Gandolina Melhem, Byron Brook, Manisha Menon, Dheeraj Soni, Simone Schüller, Karthik Siram, Etsuro Nanishi, Hélène G. Bazin, David J. Burkhart, Ofer Levy, Jay T. Evans   +16 more
doaj   +1 more source

SARS-CoV-2 vaccine-triggered autoimmunity: Molecular mimicry and/or bystander activation of the immune system [PDF]

BioImpacts, 2023
Induced autoimmunity or autoinflammatory-like conditions as a rare vaccine-related adverse event have been reported following COVID-19 vaccination.
Azam Safary, Mostafa Akbarzadeh-Khiavi, Jaleh Barar, Yadollah Omidi   +3 more
doaj   +1 more source

Studying the Immunogenic Properties of Plague Microbe Capsule Antigen F1 Conjugated with Nanoparticles of Colloid Gold and Silver

Проблемы особо опасных инфекций, 2008
Influence of nanoparticles of colloid gold (CG) and silver (CS) on immunobiological properties of antigens and possibility of their application as adjuvants for antibody formation stimulation were studied.
M. N. Kireev, T. A. Polunina, N. P. Guseva, N. A. Podboronova, Ya. M. Krasnov, T. M. Taranenko   +5 more
doaj   +1 more source

Intranasal immunization with inactivated chlamydial elementary bodies formulated in VCG-chitosan nanoparticles induces robust immunity against intranasal Chlamydia psittaci challenge

Scientific Reports, 2021
Vaccines based on live attenuated Chlamydia elementary bodies (EBs) can cause disease in vaccinated animals and the comparably safer inactivated whole EBs are only marginally protective.
Zonghui Zuo, Yongjuan Zou, Qiang Li, Yongxia Guo, Tianyuan Zhang, Jie Wu, Cheng He, Francis O. Eko   +7 more
doaj   +1 more source

Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses [PDF]

, 2008
Alum is used as a vaccine adjuvant and induces T_h2 responses and T_h2-driven antibody isotype production against co-injected antigens.
A. S. McKee, Alving, Atochina, Beutler, Bomford, Brewer, Brewer, Brogdon, Cambier, Crawford, Cunningham, F. Crawford, Gavin, Grun, Grzych, Hoebe, J. W. Kappler, J. White, Jordan, Kaisho, Kane, Kapsenberg, Kawai, Lang, Layland, Li, Liu, M. MacLeod, MacDonald, McDonald, Medzhitov, Mohrs, Morefield, Noben-Trauth, Okano, Ouyang, P. Marrack, Pearce, Pollock, Reese, Schnare, Sokolovska, Steinman, Sun, Trinchieri, Whelan   +45 more
core   +1 more source

Imiquimod 5% cream in the treatment of superficial and nodular basal cell carcinomas: study of 10 cases Tratamento tópico do carcinoma basocelular superficial e nodular pelo imiquimod creme a 5%: observação de 10 casos

Anais Brasileiros de Dermatologia, 2002
BACKGROUND: Topical treatment with 5% imiquimod cream has been demonstrated to be effective in patients with basal cell carcinoma. OBJECTIVES: In the present study, efficacy and tolerability of this treatment was analyzed in 10 patients with 13 different
Cyro Festa Neto
doaj   +1 more source

What's new in the diagnosis and management of food allergy in children? [PDF]

, 2013
This article reviews the recent advances in the diagnosis and management of IgE mediated food allergy in children. It will encompass the emerging technology of component testing; moves to standardization of the allergy food challenge; permissive diets ...
Campbell, DE, Turner, PJ
core   +1 more source