Results 201 to 210 of about 809,966 (374)

Unlocking the Gates: A Novel Diagnostic Molecule for Quantifying Efflux Levels in Gram‐Positive Bacteria

open access: yesAdvanced Healthcare Materials, EarlyView.
Efflux‐mediated resistance compromises antibiotic efficacy, yet rapid detection remains elusive. This study presents a novel phenazinium‐based diagnostic molecule for quantifying bacterial efflux levels in Gram‐positive pathogens. The optimized compound enables precise, real‐time efflux assessment using fluorescence and colorimetric techniques ...
Mrunal Patil   +15 more
wiley   +1 more source

Antigens and Adjuvants [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1968
openaire   +3 more sources

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

Injectable 2D‐MoS2‐integrated Bioadhesive Hydrogel as Photothermal‐Derived and Drug‐Delivery Implant for Colorectal Cancer Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An injectable, adhesive hydrogel integrating 2D‐MoS2 and 5‐fluorouracil (AlgNB/MoS2/5‐FU) is developed for near‐infrared‐triggered photothermal therapy and localized drug delivery. The adhesive hydrogel demonstrates superior tumor anchoring, efficient photothermal conversion, and synergistic inhibition of colorectal cancer progression, offering a ...
Xiaojun Long   +8 more
wiley   +1 more source

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth   +10 more
wiley   +1 more source

Imine Crosslinked, Injectable, and Self‐Healing Fucoidan Hydrogel with Immunomodulatory Properties

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops an injectable fucoidan‐based hydrogel with tunable properties for tissue engineering. By oxidizing fucoidan (OFu) to introduce aldehydes, imine crosslinks are formed with amine‐containing polymers, enabling self‐healing, injectability, and long‐term stability (≥28 days). The OFu‐gelatin hydrogel demonstrated biocompatibility, immune‐
Asma Talib Qureshi   +3 more
wiley   +1 more source

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