Pancreatic resection in very elderly patients: A critical analysis of existing evidence [PDF]
The aging of the population results in a rise of number of elderly patients (aged 80 years and older) with pancreatic or periampullary cancer, and more pancreatectomies could eventually be performed in such complex patients.
Moletta, Lucia +2 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
ENDOSCOPIC THIRD VENTRICULOSTOMY IN THE TREATMENT OF NORMOTENSIVE HYDROCEPHALUS. A CLINICAL CASE
Introduction. Normotensive hydrocephalus is an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain. This causes an increase in the enlargement of the ventricles and an increase in intracranial pressure.
Orest I. Palamar +4 more
doaj +1 more source
Primary Cilia in the Skin: Functions in Immunity and Therapeutic Potential
The skin is the biggest organ and provides a physical and immunological barrier against pathogen infection. The distribution of primary cilia in the skin of mice has been reported, but which cells in human skin have them has not, and we still know very ...
Manami Toriyama +5 more
doaj +1 more source
Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]
<b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson +41 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Retinol is widely used in topical skincare products to ameliorate skin aging and treat acne and wrinkles; however, retinol and its derivatives occasionally have adverse side effects, including the induction of irritant contact dermatitis.
Azusa Saika +14 more
doaj +1 more source
Effect of adjuvants on the efficiency of dimethomorph plus mancozeb (Acrobat 2 kg:ha) on the control of late blight [PDF]
Industrial adjuvants were tested in combination with dimethomorph plus mancozeb (Acrobat 2 kg/ha) in the field to investigate their efficacy on foliar late blight caused by Phytophthora infestans.
Haesaert, Geert +6 more
core +1 more source
Therapeutic approach in glioblastoma multiforme with primitive neuroectodermal tumor components: case report and review of the literature [PDF]
Glioblastoma multiforme (GBM) is the most common and aggressive malignant glioma that is treated with first-line therapy, using surgical resection followed by local radiotherapy and concomitant/adjuvant temozolomide (TMZ) treatment.
Berrios J. R. G. +12 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

