Results 31 to 40 of about 566,656 (110)

FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer

New England Journal of Medicine, 2018
BACKGROUND Among patients with metastatic pancreatic cancer, combination chemotherapy with fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) leads to longer overall survival than gemcitabine therapy.
T. Conroy, P. Hammel, M. Hebbar, M. Ben Abdelghani, A. Wei, J. Raoul, L. Choné, E. François, P. Artru, J. Biagi, T. Lecomte, E. Assenat, R. Faroux, M. Ychou, J. Volet, A. Sauvanet, G. Breysacher, F. Di Fiore, C. Cripps, P. Kavan, P. Texereau, K. Bouhier-Leporrier, F. Khemissa-Akouz, J. Legoux, B. Juzyna, S. Gourgou, C. O'Callaghan, C. Jouffroy-Zeller, P. Rat, D. Malka, F. Castan, J. Bachet   +31 more
semanticscholar   +1 more source

Abemaciclib Combined With Endocrine Therapy for the Adjuvant Treatment of HR+, HER2−, Node-Positive, High-Risk, Early Breast Cancer (monarchE)

Journal of Clinical Oncology, 2020
PURPOSE Many patients with HR+, HER2− early breast cancer (EBC) will not experience recurrence or have distant recurrence with currently available standard therapies.
S. Johnston, N. Harbeck, R. Hegg, M. Toi, Miguel Martín, Z. Shao, Qing-Yuan Zhang, J. M. Martínez Rodríguez, M. Campone, E. Hamilton, J. Sohn, V. Guarneri, M. Okada, F. Boyle, P. Neven, J. Cortés, J. Huober, A. Wardley, S. Tolaney, I. Çiçin, I. Smith, Martin Frenzel, D. Headley, Ran Wei, Belen San Antonio, M. Hulstijn, J. Cox, J. O'Shaughnessy, P. Rastogi   +28 more
semanticscholar   +1 more source

Adjuvanla artrit oluşturulmuş sıçan modelinde izole aort preparatının reaktif yanıtları ve allopürinol’ün gevşeme yanıtlarına etkisi

, 2009
Bu çalışmada sıçan adjuvant artrit modelinde, izole torasik aorta yanıtlarındaki değişiklikler ve al- u çalışmada sıçan adjuvant artrit modelinde, izole torasik aorta yanıtlarındaki değişiklikler ve al- lopürinolün gevşeme yanıtları üzerindeki etkileri ...
Dökmeci, İsmet, Hatip-Al-Khatib, İzzettin, Hatip, Funda F. Bölükbaşı, Ülker, Sibel   +3 more
core   +2 more sources

Neoadjuvant and Adjuvant Pembrolizumab in Locally Advanced Head and Neck Cancer.

New England Journal of Medicine
BACKGROUND The benefit of the addition of perioperative pembrolizumab to standard care with surgery and adjuvant therapy for patients with locally advanced head and neck squamous-cell carcinoma (HNSCC) is unclear.
R. Uppaluri, R. I. Haddad, Y. Tao, C. le Tourneau, Nancy Y. Lee, W. Westra, R. Chernock, Makoto Tahara, Kevin J. Harrington, A. Klochikhin, I. Braña, Gustavo Vasconcelos Alves, B. Hughes, M. Oliva, Iane Pinto Figueiredo Lima, T. Ueda, T. Rutkowski, Ursula Schroeder, P. Mauz, T. Fuereder, S. Laban, N. Oridate, A. Popovtzer, Nicolas Mach, Yevhen Korobko, D. Alpuim Costa, A. Hooda-Nehra, Cristina P. Rodriguez, R. B. Bell, C. Manschot, K. Benjamin, B. Gumuscu, D. Adkins   +32 more
semanticscholar   +1 more source

Vaccination with complete adjuvant-added inactivated virus vaccine of Japanese encephalitis to swine, rabbits and chicks for preventing viremia (epidemiological study on Japanese encephalitis 25) [PDF]

, 1969
As a step towards the elimination of Japanese encephalitis virus in natural surroundings, we inoculated pigs, rabbits and chicks with inactivated Japanese encephalitis vaccine supplemented with complete or incomplete Freund's adjuvant twice at one-week ...
Nagao, Yutaka, Kitamura, Naoji, Jitsunari, Fumihiko, Ogata, Masana   +3 more
core   +1 more source

Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma.

New England Journal of Medicine
BACKGROUND Adjuvant pembrolizumab therapy after surgery for renal-cell carcinoma was approved on the basis of a significant improvement in disease-free survival in the KEYNOTE-564 trial.
T. Choueiri, P. Tomczak, Se Hoon Park, B. Venugopal, T. Ferguson, S. Symeonides, J. Hajek, Yen-Hwa Chang, J. Lee, N. Sarwar, Naomi B Haas, H. Gurney, P. Sawrycki, M. Mahave, M. Gross-Goupil, Tian Zhang, John M. Burke, G. Doshi, B. Melichar, Evgeniy Kopyltsov, A. Alva, S. Oudard, Delphine Topart, H. Hammers, Hiroshi Kitamura, D. McDermott, Adriano Silva, E. Winquist, J. Cornell, Aymen Elfiky, J. Burgents, R. Perini, T. Powles   +32 more
semanticscholar   +1 more source

Adjuvant and neoadjuvant immunotherapies in hepatocellular carcinoma

Nature Reviews Clinical Oncology
Liver cancer, specifically hepatocellular carcinoma (HCC), is the sixth most common cancer and the third leading cause of cancer mortality worldwide.
J. Llovet, R. Pinyol, M. Yarchoan, Amit G. Singal, T. Marron, Myron Schwartz, Eli Pikarsky, M. Kudo, R. Finn   +8 more
semanticscholar   +1 more source

Adjuvant Pembrolizumab versus Observation in Muscle-Invasive Urothelial Carcinoma

New England Journal of Medicine
BACKGROUND Muscle-invasive urothelial carcinoma is an aggressive disease with high rates of relapse. We evaluated pembrolizumab as adjuvant therapy in patients with high-risk muscle-invasive urothelial carcinoma after radical surgery.
A. Apolo, K. Ballman, G. Sonpavde, Stephanie Berg, William Y. Kim, R. Parikh, Min Y. Teo, R. F. Sweis, D. Geynisman, P. Grivas, G. Chatta, Z. Reichert, Joseph W. Kim, Mehmet Asim Bilen, Bradley McGregor, Parminder Singh, Abhishek Tripathi, Suzanne Cole, Nicholas I Simon, Scot A Niglio, L. Ley, L. Cordes, S. Srinivas, Jiaoti Huang, Meagan Odegaard, C. Watt, D. Petrylak, J. Hoffman-Censits, Yujia Wen, Olwen Hahn, C. Mitchell, A. Tan, H. Streicher, E. Sharon, Helen Moon, Michael Woods, Susan Halabi, Gabriela Perez Burbano, M. Morris, J.E. Rosenberg   +39 more
semanticscholar   +1 more source

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.

New England Journal of Medicine, 2005
BACKGROUND Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to the extent feasible, followed by adjuvant radiotherapy. In this trial
R. Stupp, W. Mason, M. J. van den Bent, M. Weller, B. Fisher, M. Taphoorn, K. Bélanger, A. Brandes, C. Marosi, U. Bogdahn, J. Curschmann, Robert C. Janzer, S. Ludwin, T. Gorlia, A. Allgeier, D. Lacombe, J. Cairncross, E. Eisenhauer, R. Mirimanoff   +18 more
semanticscholar   +1 more source

The Role of Tomatine Adjuvant in Antigen Delivery for Cross-Presentation

, 2017
The aim of this study was to investigate the use of tomatine adjuvant to deliver soluble antigen for cross-presentation by bone marrow-derived dendritic cells (BMDCs).
Hsu, Paul Y. -J.;Wu, Ching-An;Shen, Shan-Shan;Yang, Ya-Wun, 楊雅雯   +1 more
core   +1 more source