Results 81 to 90 of about 488,339 (301)

The outcomes and quality of life of young patients undergoing adjuvant radiotherapy versus non-radiotherapy following surgery treating early FIGO stage cervical squamous cell cancer in southwestern China

Scientific Reports, 2020
Background: The incidence of cervical cancer in young women is rising, and squamous cell carcinoma makes up a great percentage of the histological types.
Lingyun Yang, Jialing Yuan, Xi Zeng, Mingrong Xi, Hongjing Wang   +4 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Effect of postoperative adjuvant radiotherapy on the prognosis of type B2 thymoma patients: A multi-center, retrospective real-world study

徐州医科大学学报
Objective To evaluate the impact of postoperative adjuvant radiotherapy on the survival benefits of patients with complete resection of type B2 thymoma, providing evidence for postoperative adjuvant radiotherapy. Methods A total of 154 patients with type
WANG Minhan, REN Xiuyu, REN Zhen, ZHOU Yun, WANG Qiang, DING Xin   +5 more
doaj   +1 more source

Meta-analysis of the influence of surgical margin and adjuvant radiotherapy on local recurrence after resection of sporadic desmoid-type fibromatosis

, 2017
Background Extra-abdominal desmoid-type fibromatosis (DF) is a rare, locally aggressive neoplasm that is usually managed conservatively.
van Broekhoven, D L M, D L M van Broekhoven, Grünhagen, D J, A Gronchi, D J Grünhagen, Bonvalot, S, J J Nuyttens, Verhoef, C, Grünhagen, D J; id_orcid, Cates, J M M, S Bonvalot, Gronchi, A, Nuyttens, J J, J M M Cates, Bramer, W M, C Verhoef, Salas, S, M L Janssen, W M Bramer, S Salas, Janssen, M L   +20 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Incidence of radiation toxicity in cervical cancer and endometrial cancer patients treated with radiotherapy alone versus adjuvant radiotherapy [PDF]

, 2012
AimThe study was made to evaluate early and late toxicity in a diversified group of patients receiving definitive or adjuvant radiotherapy in terms of clinical diagnosis and treatment methods.BackgroundRadiotherapy is a standard way of treatment in ...
Wareńczak-Florczak, Żaneta; Greater Poland Cancer Centre, Department of Gynaecological Radiotherapy and Oncology, Garbary Street 15, 61-866 Poznan, Poland, Roszak, Andrzej; Greater Poland Cancer Centre, Department of Gynaecological Radiotherapy and Oncology, Garbary Street 15, 61-866 Poznan, Poland; Department of Electroradiology, University of Medical Sciences, Poznan, Poland, Bratos, Krystyna; Greater Poland Cancer Centre, Department of Gynaecological Radiotherapy and Oncology, Garbary Street 15, 61-866 Poznan, Poland, Milecki, Piotr; Department of Electroradiology, University of Medical Sciences, Poznan, Poland; Greater Poland Cancer Centre, Department of Radiation Oncology, Garbary Street 15, 61-866 Poznan, Poland   +3 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Identification and validation of single-sample breast cancer radiosensitivity gene expression predictors

Breast Cancer Research, 2018
Background Adjuvant radiotherapy is the standard of care after breast-conserving surgery for primary breast cancer, despite a majority of patients being over- or under-treated.
Martin Sjöström, Johan Staaf, Patrik Edén, Fredrik Wärnberg, Jonas Bergh, Per Malmström, Mårten Fernö, Emma Niméus, Irma Fredriksson   +8 more
doaj   +1 more source

Adjuvant radiotherapy with brachytherapy boost in soft tissue sarcomas [PDF]

, 2017
Purpose: The standard primary treatment for soft tissue sarcoma (STS) is a wide surgical resection, preceded or followed by radiotherapy. Purpose of this retrospective study was to assess the efficacy of perioperative brachytherapy (BRT) plus ...
Gambarotti, Marco, Silvia Cammelli, Ferrari, Stefano, Gian Carlo Mattiucci, Alessandra Arcelli, Cilla, Savino, Morganti, Alessio Giuseppe, Valentini, Vincenzo, Galuppi, Andrea, Marco Gambarotti, Macchia, Gabriella, Francesco Deodato, Alberto Righi, Stefano Ferrari, Alessio Giuseppe Morganti, Frakulli, Rezarta, Ferraro, Andrea, Cortesi, Annalisa, Buwenge, Milly, Andrea Ferraro, Giuseppe Bianchi, Fabrizio Romani, Davide Donati, Farioli, Andrea, Righi, Alberto, Deodato, Francesco, Savino Cilla, Annalisa Cortesi, Romani, Fabrizio, Andrea Farioli, Bianchi, Giuseppe, Gabriella Macchia, Milly Buwenge, Vincenzo Valentini, Cammelli, Silvia, Andrea Galuppi, Arcelli, Alessandra, Donati, Davide, Rezarta Frakulli, Mattiucci, Gian Carlo   +39 more
core   +1 more source

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah, Martha E. Stewart, Nathan Maassel, James P. Stevens, Claudia R. Morris, Chris A. Rees   +5 more
wiley   +1 more source