Results 151 to 160 of about 49,397 (289)

Development of a Cutting Guide for Osteocutaneous Radial Forearm Free Flap Harvest

open access: yesThe Laryngoscope, EarlyView.
A custom radius cutting guide for osteocutaneous radial forearm free flap harvest was developed in an iterative process with six head and neck surgeons and one hand surgeon. This article details its development and use in eight patient cases. ABSTRACT Objectives The osteocutaneous radial forearm free flap (OCRFFF) is used for the reconstruction of bony
Carly Fassler   +11 more
wiley   +1 more source

Impact of WPOI‐5 on Risk of Regional Recurrence in Early Oral Cancer With pN0 Neck

open access: yesThe Laryngoscope, EarlyView.
In the present retrospective study, worst pattern of invasion category 5 (WPOI‐5) was found to be significantly associated with regional recurrence (RR) among patients with early oral cancer and pathologically negative necks after elective neck dissection. Isolated RR was seen only among patients not receiving postoperative radiotherapy (PORT), however,
Justin Hintze   +5 more
wiley   +1 more source

A new transmucosal drug delivery system for patients with breakthrough cancer pain: the fentanyl effervescent buccal tablet

open access: yesJournal of Pain Research, 2008
Enno FreyeCenter of Ambulatory Pain Medicine, Neuss-Uedesheim, GermanyAbstract: Breakthrough pain, a transitory severe pain with the background of otherwise controlled persistent pain has a prevalence between 52% and 67% in outpatients with cancer ...
Enno Freye
doaj  

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

open access: yesMacromolecular Bioscience, EarlyView.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro   +6 more
wiley   +1 more source

Integrating Nanotechnology With 3D Printing for Drug Delivery: Bone Regeneration and Beyond

open access: yesNano Select, EarlyView.
What happens when nanotechnology meets 3D printing? This review explores how their fusion transforms drug delivery and bone regeneration, creating smarter, more adaptable therapies. From nanomaterials to futuristic fabrication methods, the article maps innovations that could redefine personalized medicine and hints at the challenges researchers must ...
Felipe Sousa Siqueira   +2 more
wiley   +1 more source

Management and Outcomes of Postoperative Airway Obstruction in Patients After Tissue‐Augmentation Palatoplasty

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To characterize postoperative airway obstruction and evaluate management strategies in pediatric patients with cleft palate following tissue‐augmentation palatoplasty (TAP). Study Design Retrospective case series. Setting Single academic center. Methods Patients with obstruction within 1 year of primary TAP between 2017 and 2023 were
Pooja D. Reddy   +6 more
wiley   +1 more source

New insights into the genetic progression of cancer through longitudinal analysis of oral lesions

open access: yesThe Journal of Pathology, EarlyView.
Abstract Genetic progression models of cancer continue to determine the roadmap of carcinogenesis, although the sequence of genetic events is inferred rather than empirically determined through longitudinal analyses. Here, we present a unique longitudinal study of oral leukoplakia lesions that transformed into carcinoma.
Leon J Wils   +9 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Bilateral rostral mandibulectomy in case of a complete fracture of the pars incisiva in a Simmental fattening bull

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 9‐month‐old Simmental fattening bull with a history of anorexia, severe salivation and marked bilateral swelling of the mandible was referred to the clinic. The physical examination and radiographs revealed a bilateral complete displaced mandibular fracture involving the symphysis. Treatment consisted of rostral mandibulectomy, including the
Cassandra Eibl   +4 more
wiley   +1 more source

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