An Updated Overview of the Emerging Role of Patch and Film-Based Buccal Delivery Systems [PDF]
Pharmaceutics, 2021 Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery, anatomical and physiological aspects of oral mucosa, and various in ...
Shery Jacob +5 more
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Development, Characterization, and Ex Vivo Assessment of Elastic Liposomes for Enhancing the Buccal Delivery of Insulin [PDF]
Pharmaceutics, 2021 Buccal drug delivery is a suitable alternative to invasive routes of drug administration. The buccal administration of insulin for the management of diabetes has received substantial attention worldwide.
Santosh Bashyal +5 more
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Factors affecting the buccal delivery of deformable nanovesicles based on insulin–phospholipid complex: an in vivo investigation [PDF]
Drug Delivery, 2020 Deformable nanovesicles (DNVs) have been used in the buccal delivery of biomacromolecules due to their ability to enhance drug penetration. However, no breakthroughs have been made until now due to limited understanding of the factors affecting in vivo ...
Yuqi Yang +6 more
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Sublingual and Buccal Delivery: A Historical and Scientific Prescriptive [PDF]
PharmaceuticsIn this review, our intention was to shed some light on the history of sublingual and buccal delivery over the past 75 years. By searching the query sublingual and buccal, we noticed four steady growth periods in the number of publications between 1950 ...
Sina Bahraminejad, Hassan Almoazen
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Fast-Dissolving Nifedipine and Atorvastatin Calcium Electrospun Nanofibers as a Potential Buccal Delivery System [PDF]
Pharmaceutics, 2022 Geriatric patients are more likely to suffer from multiple chronic diseases that require using several drugs, which are commonly ingested. However, to enhance geriatric patients’ convenience, the electrospun nanofiber system was previously proven to be a
Hassa A. Alshaya +13 more
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Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin [PDF]
International Journal of Nanomedicine, 2018 You Xu,1,2 Xing Zhang,1,2 Yun Zhang,1,2 Jun Ye,1,2 Hong-Liang Wang,1,2 Xuejun Xia,1,2 Yuling Liu1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & ...
Xu Y +6 more
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Buccal Insulin Delivery Systems: Formulation Approaches, Stability Constraints, and Translational Prospects [PDF]
PharmaceuticsInsulin delivery via the buccal route has shown long-standing promise for diabetes therapy, but clinical translation remains limited. Most systems address only part of the delivery problem, whereas a viable product must simultaneously provide adequate ...
Jahanvi Patel +2 more
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Development and Characterization of Inkjet Printed Edible Films for Buccal Delivery of B-Complex Vitamins [PDF]
Pharmaceuticals, 2020 Buccal films containing two vitamins, i.e., thiamine hydrochloride (THCl) and nicotinic acid (NA), were fabricated via two-dimensional (2D) inkjet printing.
Georgios Eleftheriadis +7 more
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Development and Characterization of Chitosan Microparticles-in-Films for Buccal Delivery of Bioactive Peptides [PDF]
Pharmaceuticals, 2019 Nowadays, bioactive peptides are used for therapeutic applications and the selection of a carrier to deliver them is very important to increase the efficiency, absorption, release, bioavailability and consumer acceptance.
Patrícia Batista +4 more
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Protein Delivery Using Three-Dimensional Printing of Buccal Films: Technological Advances and Clinical Potential [PDF]
PharmaceuticsTherapeutic proteins have emerged as a cornerstone of modern medicine due to their high specificity and strong biological effects. However, delivering these proteins poses significant challenges due to their instability, susceptibility to enzymatic ...
Tejaswi Appidi +4 more
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