Results 41 to 50 of about 1,353,755 (237)

In Vitro and Ex Vivo Evaluation of Penetratin as a Non-invasive Permeation Enhancer in the Penetration of Salmon Calcitonin through TR146 Buccal Cells and Porcine Buccal Tissues

Pharmaceuticals, 2020
Buccal tissues are considered one of the potential alternative delivery route because of fast drug absorption and onset of action due to high vascularization and a non-keratinized epithelial membrane.
Taekwang Keum, Gyubin Noh, Jo-Eun Seo, Santosh Bashyal, Sangkil Lee   +4 more
doaj   +1 more source

MUCOADHESIVE BUCCAL DRUG DELIVERY SYSTEM: REVIEW ARTICLE [PDF]

, 2017
The advantage of buccal drug delivery system over the conventional and systemic formulation majority. It helps enhance the bioavailability through bypassing the first-pass metabolism effect. The mucosal surface better absorption and prolong resident time.
., Ravindrasaudagar, Sonawane, Monali, Shinkar, Dattatrey   +2 more
core   +3 more sources

Preface for buccal drug delivery theme issue [PDF]

, 2014
During the past years, buccal drug delivery has attracted the attention of researchers looking for alternative delivery routes of administration. As an alternative to oral drug delivery, the buccal mucosal route avoids the passage through the acidic ...
Morales, Javier Octavio, Morales, Javier Octavio,, McConville, Jason Thomas,, McConville, Jason Thomas   +3 more
core   +1 more source

Multiple Roles of Chitosan in Mucosal Drug Delivery: An Updated Review

Marine Drugs, 2022
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after cellulose, is the second biopolymer most abundant in nature, being the primary component of the exoskeleton of crustaceans and insects.
Paola Mura, Francesca Maestrelli, Marzia Cirri, Natascia Mennini   +3 more
doaj   +1 more source

Turning Light Into Matter: Programmable Microstructures Via Dose Control in Two‐Photon Polymerization

Advanced Optical Materials, EarlyView.
This work augments two‐photon polymerization with point‐wise dose control, enabling structures with heterogeneous material properties such as refractive index. An open source toolbox and superior calibration methodology for the refractive index pave the way for bio‐mimicking or numerically optimized structure designs, and enhance the synergy between 3D
Michał Ziemczonok, Koen Vanmol
wiley   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Desenvolvimento de estratégias farmacotécnicas para a melhoria das características biofarmacêuticas do mesilato de Saquinavir & avaliação da permeabilidade bucal do cloridrato de donepezila [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2013.Para fármacos com solubilidade aquosa limitada, estratégias farmacotécnicas visando a melhoria das ...
Caon, Thiago
core  

Chitosan based hydrogels for transmucosal drug delivery [PDF]

, 2013
The aim of this thesis was the formulation of new chitosan based delivery systems for transmucosal drug administration. Transmucosal routes, such as buccal, vaginal and nasal routes, allow the circumvention of the hepatic first pass metabolism and avoid ...
Abruzzo, Angela <1984>
core   +1 more source

Two‐Dimensional Conjugated Metal Organic Frameworks with Dual Metal Catalytic Active Sites Enhance POD Activity for Antibacterial Treatment

Advanced Science, EarlyView.
A new class of Cu, Ni bimetallic 2D cMOF (CuNi‐HHTP 2D cMOF) featuring dual catalytic sites and high delocalized electronic structure for boosting POD performance. The CuNi‐HHTP 2D‐cMOF enhances the conversion kinetics of H2O2 to ROS, which subsequently enhances antibacterial activity and accelerates the healing of oral ulcers, with macroscopic wound ...
Yixuan Lu, Qinqin Li, Yumin Chen, Shihan Zhang, Shuai Ding, Yanpei Wang, Youxing Liu, Yaru Guo, Xuliang Deng, Shaojun Guo   +9 more
wiley   +1 more source

Boosting buccal drug absorption: Mechanistic insights into bilosome-mediated delivery

International Journal of Pharmaceutics: X
Effective buccal drug delivery is limited by the barrier properties of the mucosa, necessitating innovative systems to enhance permeability without compromising tissue integrity.
Eleftheria Pantazoglou, Scarlett Zeiringer, Matteo Tollemeto, Nazanin Zanjanizadeh Ezazi, Zhongyang Zhang, Leticia Hosta-Rigau, Jette Jacobsen, Ramona Jeitler, Eva Roblegg, Line Hagner Nielsen   +9 more
doaj   +1 more source