Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance [PDF]
, 2008 Live bacterial vaccines have great promise both as vaccines against enteric pathogens and as heterologous antigen vectors against diverse diseases. Ideally, room temperature stable dry formulations of live bacterial vaccines will allow oral vaccination ...
Edwards, Alexander D. +1 more
core +1 more source
The bile salt export pump [PDF]
, 2018 Canalicular secretion of bile salts mediated by the bile salt export pump Bsep constitutes the major driving force for the generation of bile flow.
Meier, Peter +2 more
core
Association between cholesterol-phospholipid vesicles and cholesterol crystals in human gallbladder bile [PDF]
, 1989 Rapid aggregation of cholesterol-phospholipid vesicles in gallbladder bile seems to be the first event in the production of cholesterol crystals, a prerequisite for cholesterol gallstone formation.
Jüngst, Dieter +1 more
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The ulcerogenic effect of bile and bile acid in rats during immobilization stress [PDF]
The effect of different concentrations of oxen bile and individual bile acids or their sodium salts on the gastric mucosa of rats was investigated in combination with immobilization stress.
Weisener, J.
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Bile salt receptor complex activates a pathogenic type III secretion system
eLife, 2016 Bile is an important component of the human gastrointestinal tract with an essential role in food absorption and antimicrobial activities. Enteric bacterial pathogens have developed strategies to sense bile as an environmental cue to regulate virulence ...
Peng Li +6 more
doaj +1 more source
Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]
, 1993 Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Huber, P. +4 more
core
Studies on the reconstitution of the structure and function of mitochondrial inner membrane. I. Structure and function of the membrane formed by the purified complex 3 and complex IV of the mitochondrial electron transfer chain [PDF]
, 1969 In order to elucidate the molecular organization of mitochondrial inner membrane, biochemical and electron microscope observations were made on the formation of membrane structure and function by the purified complexes of the electron transfer chain of ...
Hayashi, Hideo
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Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis [PDF]
, 2006 Background/Aims: The expression of transporters involved in bile acid homeostasis is differentially regulated during obstructive cholestasis. Since the drug efflux transporter breast cancer resistance protein (BCRP) is known to transport bile acids, we ...
Adachi Y +48 more
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Lactobacillus ruminis strains cluster according to their mammalian gut source [PDF]
, 2015 peer-reviewedBackground Lactobacillus ruminis is a motile Lactobacillus that is autochthonous to the human gut, and which may also be isolated from other mammals. Detailed characterization of L. ruminis has previously been restricted to strains of human
Harris, Hugh +4 more
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