Results 41 to 50 of about 87,175 (303)

Inhibition of calcium phosphate precipitation by bile salts: a test of the Ca(2+)-buffering hypothesis.

Journal of Lipid Research, 1994
The ability of bile salts to inhibit the precipitation of either calcium hydroxyapatite or its precursor, amorphous calcium phosphate, by reducing Ca2+ activity or poisoning nascent crystals was determined.
R S Crowther, M Okido
doaj   +1 more source

Simulation study of micelle formation by bile salts [PDF]

, 2010
We report coarse-grained, implicit-solvent simulations of aqueous solutions of bile salts. The parameters in our model were optimized to reproduce some of the experimentally known behavior of dihydroxy bile salts at “physiological” temperature and ...
Affentranger, Ana Vila Verde, Andreatta, Bolhuis, Carey, Cooke, Daan Frenkel, Fuhrhop, Fukunishi, Funasaki, Garidel, Geyer, Gustafsson, Humphrey, Kawamura, Leng, Limbach, Lyubartsev, Marinari, Marques, Mazer, Mukhopadhyay, Oakenfull, Partay, Partay, Pool, Roda, Small, Sugita, Sugita, Warren, Yoshii   +31 more
core   +1 more source

Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts

Scientific Reports, 2017
Bile salts have potent detergent properties and damaging effects on cell membranes, leading to liver injury. However, the molecular mechanisms for the protection of hepatocytes against bile salts are not fully understood.
Yoshito Ikeda, Shin-ya Morita, Tomohiro Terada   +2 more
doaj   +1 more source

Bile resistance mechanisms in Lactobacillus and Bifidobacterium

Frontiers in Microbiology, 2013
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Most of the probiotic bacteria currently available in the market belong to the genera Lactobacillus and Bifidobacterium, and specific ...
Lorena eRuiz, Abelardo eMargolles, Borja eSánchez   +2 more
doaj   +1 more source

Distribution of mixtures of bile salt taurine conjugates between lecithin-cholesterol vesicles and aqueous media: an empirical model

Journal of Lipid Research, 1997
Bile salts are surfactants that partition into phospholipid bilayers. When liposomes or membranes are exposed to mixed solutions of bile salts, the more hydrophobic bile salt species associate preferentially with the lipid bilayer.
D M Heuman
doaj   +1 more source

Effect of Intraduodenal Bile and Na-Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Secretin, Pancreatic Polypeptide, and Gastrin in Man [PDF]

, 1990
The effect of intraduodenally administered cattle bile (CB) and Na-taurodeoxycholate (TDC) on basal pancreatic secretion and plasma levels of secretin, pancreatic polypeptide (PP), and gastrin were investigated on two separate days in 10 fasting ...
A. Scharl, Aronchick C A, Bjornsson O G, Bondesen S, Burhol P G, Burhol P G, Burhol P G, Carey M C, Davies H A, Dragstedt L R, F. Fiedler, Fahrenkrug J, Flaten O, Florholmen J, Forell M M, Forell M M, Greenberg G R, Gries E, Grossman M I, Hanssen L E, Hartmann W, Hunter W M, I. Hempen, J. Teufel, Jorde R, Konturek S J, Lehnert P, Londong W, Lonovics J, Malagelada J-R., Malagelada J-R., Miyasaka K, Miyazaki K, Moreland H J, Morris B J, Osnes M, Osnes M, Otte M, P. G. Burhol, P. Lehnert, Petersen H, R. L. Riepl, Scatchard G, Schaffalitzky de Muckadell O B, Schwartz T W, Thomas J E, Wormsley K G   +46 more
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A phylogenetic survey of biliary lipids in vertebrates1,

Journal of Lipid Research, 2005
Biliary lipids (bile salts, phospholipids, cholesterol, plant sterols) were determined in 89 vertebrate species (cartilaginous and bony fish, reptiles, birds, and mammals), and individual phospholipid classes were measured in 35 species.
Antonio Moschetta, Fang Xu, Lee R. Hagey, Gerard P. van Berge-Henegouwen, Karel J. van Erpecum, Jos F. Brouwers, Jonathan C. Cohen, Molly Bierman, Helen H. Hobbs, Joseph H. Steinbach, Alan F. Hofmann   +10 more
doaj   +1 more source

Bile Salt Hydrolase Degrades β-Lactam Antibiotics and Confers Antibiotic Resistance on Lactobacillus paragasseri

Frontiers in Microbiology, 2022
Bile salt hydrolase (BSH) is a well-characterized probiotic enzyme associated with bile detoxification and colonization of lactic acid bacteria in the human gastrointestinal tract.
Hiroyuki Kusada, Masanori Arita, Masanori Tohno, Masanori Tohno, Hideyuki Tamaki, Hideyuki Tamaki   +5 more
doaj   +1 more source

Bile salts in submicellar concentrations promote bidirectional cholesterol transfer (exchange) as a function of their hydrophobicity.

Journal of Lipid Research, 1990
Cholesterol, despite its poor solubility in aqueous solutions, exchanges efficiently between membranes. Movement of cholesterol between different subcellular membranes in the hepatocyte is necessary for assembly of lipoproteins, biliary cholesterol ...
ZR Vlahcevic, EC Gurley, DM Heuman, PB Hylemon   +3 more
doaj   +1 more source

Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis

Cells, 2020
Hydrophobic bile salts are considered to promote liver fibrosis in cholestasis. However, evidence for this widely accepted hypothesis remains scarce. In established animal models of cholestasis, e.g., by Mdr2 knockout, cholestasis and fibrosis are both ...
Simon Hohenester, Veronika Kanitz, Andreas E. Kremer, Coen C. Paulusma, Ralf Wimmer, Helen Kuehn, Gerald Denk, David Horst, Ronald Oude Elferink, Ulrich Beuers   +9 more
doaj   +1 more source