Results 11 to 20 of about 1,353,755 (237)

Development and Optimization of Ionic Strength-Responsive Lipid–Polymer Hybrid Nanoparticles for Buccal Protein Delivery [PDF]

Pharmaceutics
Background: Oral protein delivery is a major challenge in the field of pharmaceutical technology due to poor stability and limited permeability through intestinal barriers.
Eslam Ramadan, Nooh Mdrmah, Martin Deák, Norbert Varga, Edit Csapó, Tamás Sovány, Katalin Kristó   +6 more
doaj   +2 more sources

Development and Characterization of Dissolving Microneedles for the Buccal Delivery of Cannabidiol (CBD) [PDF]

Micromachines
This study aimed to develop dissolving microneedles (MNs) for the buccal delivery of cannabidiol (CBD). CBD is a non-psychotomimetic phytocannabinoid with anti-inflammatory and anxiolytic properties.
Eleni Paganopoulou, Emmanouil Tzimtzimis, Dimitrios Tzetzis, Emmanuel Panteris, Chrysanthi Bekiari, Nikolaos Bouropoulos, Christos Cholevas, Zeeshan Ahmad, Paraskevi Kyriaki Monou, Dimitrios G. Fatouros   +9 more
doaj   +2 more sources

Pharmacokinetic Aspects of Nanoparticle-in-Matrix Drug Delivery Systems for Oral/Buccal Delivery [PDF]

Frontiers in Pharmacology, 2019
Oral route maintains its predominance among the ones used for drug delivery, especially when medicines are self-administered. If the dosage form is solid, therapy gains in dose precision and drug stability.
Renata Carvalho Feitosa, Renata Carvalho Feitosa, Danilo Costa Geraldes, Danilo Costa Geraldes, Viviane Lucia Beraldo-de-Araújo, Juliana Souza Ribeiro Costa, Juliana Souza Ribeiro Costa, Laura Oliveira-Nascimento   +7 more
doaj   +2 more sources

Formulation and Characterization of Captopril-Loaded Chitosan Mucoadhesive Buccal Films with Different Permeation-Enhancing Components [PDF]

Pharmaceutics
Background/Objectives: The buccal mucosa offers a promising non-invasive route for systemic drug delivery, particularly for hydrophilic compounds like captopril (CAP), which exhibit low permeability and are subject to gastrointestinal instability and ...
Hala Rayya, Raghad Alsheikh, Dániel Nemes, Lajos Nagy, Géza Regdon, Ildikó Bácskay, Krisztián Pamlényi, Katalin Kristó   +7 more
doaj   +2 more sources

A new transmucosal drug delivery system for patients with breakthrough cancer pain: the fentanyl effervescent buccal tablet

Journal of Pain Research, 2008
Enno FreyeCenter of Ambulatory Pain Medicine, Neuss-Uedesheim, GermanyAbstract: Breakthrough pain, a transitory severe pain with the background of otherwise controlled persistent pain has a prevalence between 52% and 67% in outpatients with cancer ...
Enno Freye
doaj   +1 more source

Innovative Buccal Nanofibers for Dual Delivery of Tadalafil and Dapoxetine for Erectile Dysfunction and Premature Ejaculation Conditions [PDF]

Pharmaceuticals
Background: Erectile dysfunction (ED) and premature ejaculation (PE) are prevalent conditions affecting men’s sexual health, for which tadalafil and dapoxetine have shown promise in their treatment, respectively.
Ali A. Alamer, Khulud A. Alsulami, Abdullah A. Alshehri, Fahad A. Almughem, Nojoud Al Fayez, Meshal K. Alnefaie, Ahmed A. Almulaifi, Alhassan H. Aodah, Essam A. Tawfik   +8 more
doaj   +2 more sources

Permeability of Buccal Mucosa

Pharmaceutics, 2021
The buccal mucosa provides an alternative route of drug delivery that can be more beneficial compared to other administration routes. Although numerous studies and reviews have been published on buccal drug delivery, an extensive review of the ...
Apipa Wanasathop, Priya B Patel, Hyojin A. Choi, S. Kevin Li   +3 more
doaj   +1 more source

Aerosil in Solid-state Buccal Film for Improved and Sustained Delivery of Valsartan: Molecular Docking Studies [PDF]

Chemical and Biochemical Engineering Quarterly, 2023
To overcome low oral bioavailability and short biological half-life, improved and sustained buccal delivery of valsartan has been proposed. Valsartan film with colloidal silicon dioxide has been prepared using HPMC as mucoadhesive polymer matrix by ...
R. Swain, S. Nandi, P. Bardhan, S. S. Swain, S. Mohapatra, S. Mallick   +5 more
doaj   +1 more source

Hetrocyclic methacrylate systems as vehicles for the release of active species. [PDF]

, 2007
PhDThe room temperature polymerising heterocyclic polymer system, poly(ethyl methacrylate)/tetrahydrofurfuryl methacrylate (PEM/THFM) has been shown previously to be biocompatible and supported tissue repair, specifically for bone and cartilage ...
Hoque, Shahma
core   +4 more sources

Bioadhesive polymers, permeation enhancers and types of dosage forms for buccal drug delivery [PDF]

, 2021
The buccal delivery is defined as the drug administration through the mucosal membranes lining the cheeks (buccal mucosa). The main impediment to the use of many hydrophilic macromolecular drugs as potential therapeutic agents is their inadequate and ...
Satla, Shobha Rani, Bairi, Agaiah Goud, Samanthula, Kumara Swamy   +2 more
core   +1 more source