Results 11 to 20 of about 28,615 (245)
A novel dosage form for buccal administration of bupropion [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2015 Bupropion is an antidepressant used in the treatment of smoking. The purpose of this study was to prepare controlled-release hydrogel films for buccal administration of bupropion and investigate its physicochemical and cytotoxic properties.
Nilsa Maria Galvão Almeida +5 more
doaj +3 more sources
Hypoglycemic Effect of Pleurotus citrinopileatus and Hericium erinaceus Buccal Tablets on Diabetic Mice [PDF]
BiologyDiabetes mellitus poses a global health challenge, necessitating natural adjuvants with minimal side effects. The aims of this study were to optimize the concentrations of chromium (Cr), zinc (Zn), and germanium (Ge) in the liquid fermentation media of ...
Zhongyi Yang +8 more
doaj +2 more sources
Pharmaceutics, 2021 Buccal drug delivery is a suitable alternative to invasive routes of drug administration. The buccal administration of insulin for the management of diabetes has received substantial attention worldwide.
Santosh Bashyal +5 more
doaj +1 more source
Pharmacokinetics of vaginal versus buccal misoprostol for labor induction at term
Clinical and Translational Science, 2022 The IMPROVE study (NCT02408315) compared the efficacy and safety of vaginal and buccal administration of misoprostol for full‐term, uncomplicated labor induction. This report compares the pharmacokinetics of misoprostol between vaginal and buccal routes.
Yana Vorontsova +10 more
doaj +1 more source
Significant hypotension following buccal midazolam administration [PDF]
BMJ Case Reports, 2010 Buccal midazolam is a rescue medication to reduce the duration of or stop an epileptic seizure, and is used to prevent status epilepticus. It is available in various forms, including a buccal preparation with a strength of 10 mg/1 ml. Midazolam is a licensed medication, but the buccal formulation is currently used off-licence.
Maria, Kensche +2 more
openaire +2 more sources
Nano Biomedicine and Engineering, 2021 The present study was conducted to evaluate the impact of calcium oxide-nanoparticles (CaO-NPs) administration at different concentrations on the epithelial thickness, papilla length and number of blood vessels of male Wister rats' buccal mucosa, and the
Bushra Habeeb Al-Maula +5 more
doaj +1 more source
Absolute Bioavailability of Microdosed Midazolam After Buccal Administration Is Dependent on Buccal Exposure Time [PDF]
The Journal of Clinical Pharmacology, 2020 AbstractMidazolam is an established probe drug to assess cytochrome P450 3A activity (phenotyping). Microdosed midazolam is increasingly used for this purpose; a buccal formulation might be of advantage, but buccal absorption might occur. We therefore tested in a single‐center, open‐label clinical trial with 12 healthy volunteers the absolute ...
Jana Grass +5 more
openaire +2 more sources
Pharmaceutics, 2021 The buccal mucosa provides an alternative route of drug delivery that can be more beneficial compared to other administration routes. Although numerous studies and reviews have been published on buccal drug delivery, an extensive review of the ...
Apipa Wanasathop +3 more
doaj +1 more source
Midazolam pharmacokinetics following intravenous and buccal administration [PDF]
British Journal of Clinical Pharmacology, 1998 Aims Midazolam has good anxiolytic qualities and is a well established premedication agent before anaesthesia or short surgical procedures. The objective of the present study was to determine pharmacokinetic data from individual plasma concentration profiles obtained following intravenous and buccal administration of midazolam.
R, Schwagmeier +2 more
openaire +2 more sources
An Updated Overview of the Emerging Role of Patch and Film-Based Buccal Delivery Systems
Pharmaceutics, 2021 Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery, anatomical and physiological aspects of oral mucosa, and various in ...
Shery Jacob +5 more
doaj +1 more source