Results 211 to 220 of about 49,397 (289)

Community‐onset pediatric status epilepticus: Barriers to care and outcomes in a real‐world setting

open access: yesEpilepsia, Volume 66, Issue 3, Page 725-738, March 2025.
Abstract Objective Status epilepticus (SE) is a neurological emergency in childhood, often leading to neuronal damage and long‐term outcomes. The study aims to identify barriers in the pre‐hospital and in‐hospital management of community‐onset pediatric SE and to evaluate the effectiveness of pediatric scores on outcomes prediction.
Anna Fetta   +12 more
wiley   +1 more source

Prognostic factors and impact of management strategies for status epilepticus: The STEPPER study in the Emilia‐Romagna region, Italy

open access: yesEpilepsia, Volume 66, Issue 3, Page 753-767, March 2025.
Abstract Objective The STEPPER (Status Epilepticus in Emilia‐Romagna) study aimed to investigate the clinical characteristics, prognostic factors, and treatment approaches of status epilepticus (SE) in adults of the Emilia‐Romagna region (ERR), Northern Italy.
Lidia Di Vito   +56 more
wiley   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

open access: yesEpilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher   +1 more
wiley   +1 more source

Pharmacokinetics and 180‐day safety of diazepam nasal spray in pediatric patients with epilepsy aged 2–5 years

open access: yesEpilepsia, EarlyView.
Abstract Objective Benzodiazepine immediate‐use seizure medications (ISMs; also called rescue therapies) are used to treat seizure clusters/acute repetitive seizures in patients with epilepsy. In the United States, diazepam nasal spray is an approved ISM for patients ≥2 years of age.
Eric B. Segal   +7 more
wiley   +1 more source

Commentary: No-test medication abortion: A sample protocol for increasing access during a pandemic and beyond. [PDF]

open access: yes, 2020
Atrio, Jessica M   +10 more
core   +1 more source

Application of an artificial intelligence–assisted electronic stethoscope for evaluating swallowing function decline across age groups and sex in Japan

open access: yesGeriatrics &Gerontology International, EarlyView.
Pharyngeal clearance time measured by a neck‐worn electronic stethoscope (NWES) became significantly prolonged in older adults, suggesting the potential of the NWES as a noninvasive, quantitative tool for assessing age‐related changes in swallowing function. Aim This preliminary investigation examined whether pharyngeal clearance time (PCT) measured by
Koichiro Matsuo   +6 more
wiley   +1 more source

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