Results 261 to 270 of about 49,397 (289)
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Development of mucoadhesive patches for buccal administration of ibuprofen
Journal of Controlled Release, 2004A new formulation for topical administration of drugs in the oral cavity has been developed using several film-forming and mucoadhesive polymers. The films have been evaluated in terms of swelling, mucoadhesion and organoleptic characteristics. The best film, containing polyvinylpyrrolidone (PVP) as film-forming polymer and carboxymethylcellulose ...
PERIOLI, Luana +6 more
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Bioavailability of flurbiprofen following buccal administration.
Pharmaceutical research, 1991The buccal absorption of flurbiprofen was evaluated in nine normal volunteers. Twenty milliliters of 2.5 mg/ml flurbiprofen solution (pH 8.03) was administered as a 1-min mouthwash or a 5-min mouthwash or swallowed. Serum was harvested from blood samples taken at specified times over a 12-hr period.
Steven R. Pollock, Dennis J. Stalker
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Development of Mucoadhesive Patches for Buccal Administration of Carvedilol
Current Drug Delivery, 2007A buccal patch for systemic administration of carvedilol in the oral cavity has been developed using two different mucoadhesive polymers. The formulations were tested for in vitro drug permeation studies, buccal absorption test, in vitro release studies, moisture absorption studies and in vitro bioadhesion studies.
K. Chandrasekhar +3 more
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A REVIEW ON BUCCAL MUCOSAL ROUTE OF DRUG ADMINISTRATION
INDIAN DRUGS, 2016Oral route is the most preferred rote of drug administration. In oral route buccal mucosal route is one of the advantageous routes of drug administration. This route provides direct access to systemic circulation through the jugular vein, bypassing the first pass hepatic metabolism, which leads to high bioavailability.
G Bhatt +3 more
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Development of an Insulin Nano-delivery System through Buccal Administration
Current Drug Delivery, 2022Aim: The aim of the study was to develop a new nano-delivery system for buccal administration of insulin. Background: Biodegradable polymeric nanoparticles (PNPs) had undergone countless breakthroughs in drug delivery systems. The main objective of PNPs application in delivering and carrying different promising drugs is to make sure that the drugs ...
Ayat Bozeya +2 more
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Systemic uptake of buprenorphine after buccal administration in cats
Veterinary Anaesthesia and Analgesia, 2002Administration of drugs to cats can be challenging and simple but effective techniques would be attractive to the owners. The purpose of this study was to compare the pharmacokinetics of buprenorphine (B) after buccal administration, and compare these to data previously collected from the same colony of cats after IV and IM injection.
Sheilah A. Robertson +3 more
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Buccal versus intravaginal misoprostol administration for cervical ripening
American Journal of Obstetrics and Gynecology, 2002The purpose of this study was to compare the efficacy of misoprostol that is administered in the buccal pouch with the intravaginal route of administration.One hundred fifty-seven pregnant women with a singleton live gestation, Bishop score of
Stephen J. Carlan +2 more
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Development of chitosan sponges for buccal administration of insulin
Carbohydrate Polymers, 2007Abstract This paper describes the development of a new highly porous, flexible device for buccal peptide administration by a very simple and mild casting/freeze-drying procedure. It consists of a mucoadhesive chitosan layer containing the peptide drug and an impermeable protective layer made of ethylcellulose.
María J. Alonso +3 more
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Absorption behavior of etilefrine after buccal administration in rats
International Journal of Pharmaceutics, 2018Etilefrine hydrochloride (ET-HCl) is used in the treatment of hypotension. Dosage forms of orally administered tablets and parenteral injections are clinically available, but exhibit unfavorable characteristics, including cardiac toxicity, headaches, and damage at the injection site for the parenteral dosage form, and initially high plasma levels, fast
Osamu Sakata, Hiraku Onishi
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Pharmacokinetics of Ciclopirox Olamine after Buccal Administration in Rabbits
Current Drug Delivery, 2017Prevalence of oral mucosal fungal infections increases with the frequent administration of antibiotics, corticosteroids and immunosuppressive drugs. Therapeutically used antifungals are usually associated with a variety of drug interactions.
Ivana Lukášová +8 more
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