Results 31 to 40 of about 28,615 (245)

Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration

Frontiers in Pharmacology, 2019
The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required ...
Susan Hua, Susan Hua
doaj   +1 more source

Efficacy of Inferior Mandibular Nerve Block (IANB) with Articaine Infiltration Versus Lidocaine Infiltration Administered inTeeth with Irreversible Pulpitis

Journal of Gandhara Medical and Dental Sciences, 2023
OBJECTIVES To compare the efficacy of (Inferior mandibular nerve block) IANB with Lidocaine infiltration versus with articaine infiltration in patients with irreversible pulpitis. METHODOLOGY An observational cross-sectional study was conducted in
Afifa Hemani, Muhammad Saqib, Sabeen Masood, Haroon Rashid, Maliha Naveed   +4 more
doaj   +1 more source

Formulation and Evaluation of Biopolymer Based Buccal Film of Diclofenac Sodium

Journal of Basic and Applied Research in Biomedicine, 2022
Buccal drug delivery gives easier and safe method of drug administration because in case of toxicity it can be terminated by simply removing the dosage form from buccal cavity.
Pooja Kashid, Amit Jadhav, Nagesh Aloorkar   +2 more
doaj   +2 more sources

Facilitated Buccal Insulin Delivery via Hydrophobic Ion-Pairing Approach: In vitro and ex vivo Evaluation

International Journal of Nanomedicine, 2021
Santosh Bashyal,1 Jo-Eun Seo,1 Taekwang Keum,1,2 Gyubin Noh,1,2 Shrawani Lamichhane,1,2 Jeong Hwan Kim,1,2 Chang Hyun Kim,3 Young Wook Choi,3 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic ...
Bashyal S, Seo JE, Keum T, Noh G, Lamichhane S, Kim JH, Kim CH, Choi YW, Lee S   +8 more
doaj  

To Compare the Efficacy of Preoperative Oral Medication of Ibuprofen and Ketorolac on Anesthetic Efficacy of Maxillary Buccal Infiltration Using Buffered 2% Lidocaine with 1:100,000 Adrenaline with Irreversible Symptomatic Pulpitis: A Prospective Clinical Study [PDF]

Dental Journal of Advance Studies
Aim: To assess the effects of ibuprofen and ketorolac, two preoperative oral medications on the effectiveness of anesthesia for maxillary buccal infiltration with buffered 2% lidocaine and 1:100,000 adrenaline in patients with irreversible symptomatic ...
Neha Menrai, Sameer Makkar, Sandeep Gupta, Ajay Aryan, Chetna Tarnach   +4 more
doaj   +1 more source

Ultrasound-Guided Extraoral Removal of Extraparenchymal Sialoliths Caused by Acute Parotitis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Migration of sialoliths is extremely rare and is presumed to be a consequence of abscess formation. We report a minimally invasive, ultrasound-guided, extraoral approach for the removal of extraparenchymal sialoliths caused by acute parotitis.
Toshinori Iwai, Satomi Sugiyama, Yuichiro Hayashi, Makoto Hirota, Kenji Mitsudo   +4 more
doaj   +1 more source

Mucoadhesive Tablets for Buccal Administration Containing Sodium Nimesulide

Drug Delivery, 2004
The possibility of improving the flux of nimesulide across the buccal mucosa using the drug in the form of a sodium salt was investigated in our study. The salt form may increase to flux across buccal membrane, starting from a suspension; its lower permeation coefficient is compensated by a higher concentration gradient.
MAFFEI, PAOLA, LOMBARDI BORGIA, SIMONE, SFORZINI, ANNALISA, BERGAMANTE, VALENTINA, CESCHEL, GIANCARLO, FINI, ADAMO, RONCHI C.   +6 more
openaire   +4 more sources

Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism

Pharmaceutics, 2019
Many new chemical entities are discovered with high therapeutic potential, however, many of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility and/or poor membrane permeation characteristics. The latter is mainly due to
Bianca Peterson, Morné Weyers, Jan H. Steenekamp, Johan D. Steyn, Chrisna Gouws, Josias H. Hamman   +5 more
doaj   +1 more source

Development of Tizanidine HCl-Meloxicam loaded mucoadhesive buccal films: In-vitro and in-vivo evaluation. [PDF]

PLoS ONE, 2018
The purpose of the study was to develop Tizanidine HCl (TZN) and Meloxicam (MLX) loaded bilayer mucoadhesive films intended for buccal administration, aiming to enhance the bioavailability.
Muhammad Zaman, Muhammad Hanif, Zaib Ali Shaheryar   +2 more
doaj   +1 more source

Concept for a Unidirectional Release Mucoadhesive Buccal Tablet for Oral Delivery of Antidiabetic Peptide Drugs Such as Insulin, Glucagon-like Peptide 1 (GLP-1), and their Analogs

Pharmaceutics, 2023
Injectable peptides such as insulin, glucagon-like peptide 1 (GLP-1), and their agonists are being increasingly used for the treatment of diabetes. Currently, the most common route of administration is injection, which is linked to patient discomfort as ...
Anubhav Pratap-Singh, Yigong Guo, Alberto Baldelli, Anika Singh   +3 more
doaj   +1 more source