Results 151 to 160 of about 2,076,286 (311)

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

CUTANEOUS ALLERGY FOLLOWING DIPHTHERIA ANATOXIN ADMINISTRATION [PDF]

BMJ, 1928
openaire   +2 more sources

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

Other title: Capitol Complex Map; Other title: Kansas Department of Administration, Division of Facilities Management map of Capitol Complex parking; Other title: Division of Facilities Management map of Capitol Complex parking

, 2014
Revised January 2014; application/pdf; Title supplied by Kansas Department of Administration website.A map of the Kansas State Capitol grounds and the surrounding area as viewed on the Kansas Department of Administration, Division of Facilities ...
Kansas. Department of Administration. Division of Facilities Management.
core   +1 more source

Irrigation administration report.

Mode of access: Internet.Continued by: Bombay (India : State). Irrigation administration report.1899/1900-1928/29 include report for Sind, later published separetely as Sind (Pakistan). Public Works Dept.
Bombay (India : State). Public Works Department., Bombay (India : State). Public Works Department. Irrigation works, accounts and financial statements., Bombay (India : State). Public Works Department. Administration report of irrigation works.   +2 more
core  

Other title: Republican River Compact Administration Documents, 2011-2013

, 2011
application/pdfThis is an incomplete collection of documents by and about the Republican River Compact Administration and the Republican River Compact from 2011 through 2013.
Republican River Compact Administration.
core  

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice

Advanced Science, EarlyView.
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li, Hongzheng Lin, Sheng Yu, Yunhui Liao, Teng Huang, Zeyu Xiao, Wei Lu   +6 more
wiley   +1 more source

Case Report: Hidden danger in breast eczematous lesions: cutaneous metastasis from silent lung adenocarcinoma misdiagnosed as Paget's disease. [PDF]

Front Oncol
Gong Z, Chen Y, Xue B, Zhang Y, Cheng H, Jia X, Liang S, Wang X.   +7 more
europepmc   +1 more source