Results 1 to 10 of about 399,843 (120)

Assessing the impact of aging and blood pressure on dermal microvasculature by reactive hyperemia optical coherence tomography angiography

open access: yesScientific Reports, 2021
Visualization and quantification of the skin microvasculature are important for studying the health of the human microcirculation. We correlated structural and pathophysiological changes of the dermal capillary-level microvasculature with age and blood ...
Michael Wang-Evers   +11 more
doaj   +1 more source

Spiny Hyperkeratosis-Like Follicular Mycosis Fungoides: A Case Report [PDF]

open access: yesMiddle East Journal of Cancer, 2023
Folliculotropic mycosis fungoides (FMF) is a rare variant of cutaneous T-cell lymphoma which is categorized as a separate entity. In histopathology, malignant lymphocytes selectively surround and infiltrate hair follicles.
Shatila Torabi   +3 more
doaj   +1 more source

Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis

open access: yesStem Cell Research & Therapy, 2021
Background Hypertrophic scar (HS) is a fibro-proliferative disorder of dermis after burn or trauma and usually leads to esthetic disfiguration and functionary impairment for patients.
Yan Li   +13 more
doaj   +1 more source

Autologous Scar-Related Tissue Combined with Skin Grafting for Reconstructing Large Area Burn Scar

open access: yesJournal of Investigative Surgery, 2022
Background This study introduced a novel method to reconstruct large areas of scarring caused by burns via combining autologous scar-related tissue with spit-thickness skin grafting (ASTCS).
Zhuoqun Fang   +7 more
doaj   +1 more source

The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway

open access: yesiScience, 2023
Summary: Circadian clock controls daily behavior and physiology. The activity of various signaling pathways affects clock gene expression. Here, we show that the core circadian clock gene CRY1 is a direct target of the Hippo pathway effector YAP.
Abdelhalim Azzi   +5 more
doaj   +1 more source

RETRACTED ARTICLE: Adipose tissue-derived stem cells suppress hypertrophic scar fibrosis via the p38/MAPK signaling pathway

open access: yesStem Cell Research & Therapy, 2016
Background Hypertrophic scars (HS) generally occur after injury to the deep layers of the dermis, resulting in functional deficiency for patients. Growing evidence has been identified that the supernatant of adipose tissue-derived stem cells (ADSCs ...
Yan Li   +14 more
doaj   +1 more source

Evaluation of clinical risk factors for systemic antimony treatment failure in patients with acute cutaneous leishmaniasis referred to dermatology clinics of Mashhad University of Medical Sciences, Iran [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2023
Background: Systemic or topical form of pentavalent antimony compounds such as Meglumine Antimoniate (MA) are used as Standard treatment for cutaneous leishmaniasis (CL).
Yalda Nahidi   +5 more
doaj   +1 more source

miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas

open access: yesJournal of Extracellular Vesicles, 2020
Exosomes, or small extracellular vesicles (sEVs), serve as intercellular messengers with key roles in normal and pathological processes. Our previous work had demonstrated that Dsg2 expression in squamous cell carcinoma (SCC) cells enhanced both sEV ...
Joseph P. Flemming   +12 more
doaj   +1 more source

Recalcitrant Cutaneous Mastocytosis Treated With Genetically Informed Targeted Therapy: A Case Report

open access: yesInternational Journal of Dermatology and Venerology, 2023
Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason   +7 more
doaj   +1 more source

CDIP1-BAP31 Complex Transduces Apoptotic Signals from Endoplasmic Reticulum to Mitochondria under Endoplasmic Reticulum Stress

open access: yesCell Reports, 2013
Resolved endoplasmic reticulum (ER) stress response is essential for intracellular homeostatic balance, but unsettled ER stress can lead to apoptosis.
Takushi Namba   +8 more
doaj   +1 more source

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