Results 1 to 10 of about 567,722 (314)

Assessing the impact of aging and blood pressure on dermal microvasculature by reactive hyperemia optical coherence tomography angiography

Scientific Reports, 2021
Visualization and quantification of the skin microvasculature are important for studying the health of the human microcirculation. We correlated structural and pathophysiological changes of the dermal capillary-level microvasculature with age and blood ...
Michael Wang-Evers, Malte J. Casper, Joshua Glahn, Tuanlian Luo, Abigail E. Doyle, Daniel Karasik, Anne C. Kim, Weeranut Phothong, Neera R. Nathan, Tammy Heesakker, Garuna Kositratna, Dieter Manstein   +11 more
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Spiny Hyperkeratosis-Like Follicular Mycosis Fungoides: A Case Report [PDF]

Middle East Journal of Cancer, 2023
Folliculotropic mycosis fungoides (FMF) is a rare variant of cutaneous T-cell lymphoma which is categorized as a separate entity. In histopathology, malignant lymphocytes selectively surround and infiltrate hair follicles.
Shatila Torabi, Sara Fakhraei, Naser Tayebi Meibodi, Farnaz Ahmadpour   +3 more
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Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis

Stem Cell Research & Therapy, 2021
Background Hypertrophic scar (HS) is a fibro-proliferative disorder of dermis after burn or trauma and usually leads to esthetic disfiguration and functionary impairment for patients.
Yan Li, Jian Zhang, Jihong Shi, Kaituo Liu, Xujie Wang, Yanhui Jia, Ting He, Kuo Shen, Yunchuan Wang, Jiaqi Liu, Wei Zhang, Tongtao Wang, Zhao Zheng, Dahai Hu   +13 more
doaj   +1 more source

Autologous Scar-Related Tissue Combined with Skin Grafting for Reconstructing Large Area Burn Scar

Journal of Investigative Surgery, 2022
Background This study introduced a novel method to reconstruct large areas of scarring caused by burns via combining autologous scar-related tissue with spit-thickness skin grafting (ASTCS).
Zhuoqun Fang, Jun Li, Kejia Wang, Ting He, Hongtao Wang, Songtao Xie, Xuekang Yang, Juntao Han   +7 more
doaj   +1 more source

The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway

iScience, 2023
Summary: Circadian clock controls daily behavior and physiology. The activity of various signaling pathways affects clock gene expression. Here, we show that the core circadian clock gene CRY1 is a direct target of the Hippo pathway effector YAP.
Abdelhalim Azzi, Zhipeng Tao, Yang Sun, Hannah Erb, Carla Guarino, Xu Wu   +5 more
doaj   +1 more source

RETRACTED ARTICLE: Adipose tissue-derived stem cells suppress hypertrophic scar fibrosis via the p38/MAPK signaling pathway

Stem Cell Research & Therapy, 2016
Background Hypertrophic scars (HS) generally occur after injury to the deep layers of the dermis, resulting in functional deficiency for patients. Growing evidence has been identified that the supernatant of adipose tissue-derived stem cells (ADSCs ...
Yan Li, Wei Zhang, Jianxin Gao, Jiaqi Liu, Hongtao Wang, Jun Li, Xuekang Yang, Ting He, Hao Guan, Zhao Zheng, Shichao Han, Maolong Dong, Juntao Han, Jihong Shi, Dahai Hu   +14 more
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miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas

Journal of Extracellular Vesicles, 2020
Exosomes, or small extracellular vesicles (sEVs), serve as intercellular messengers with key roles in normal and pathological processes. Our previous work had demonstrated that Dsg2 expression in squamous cell carcinoma (SCC) cells enhanced both sEV ...
Joseph P. Flemming, Brianna L. Hill, Mohammed W. Haque, Jessica Raad, Claudine S. Bonder, Larry A. Harshyne, Ulrich Rodeck, Adam Luginbuhl, James K. Wahl, Kenneth Y. Tsai, Peter J. Wermuth, Andrew M. Overmiller, Mỹ G. Mahoney   +12 more
doaj   +1 more source

Revisiting Imiquimod for Treatment of Folliculotropic Mycosis Fungoides: A Case Report and Review of the Literature

Dermatology and Therapy, 2019
Folliculotropic mycosis fungoides (FMF) is an aggressive variant of mycosis fungoides (MF) characterized by infiltration of the hair follicle epithelium by neoplastic T cells.
Doaa Shalabi, Nish Vadalia, Neda Nikbakht   +2 more
doaj   +1 more source

Myristoylated Cathelicidin-DM Fused With ANG1-7: A Novel Self-Assembling Antimicrobial Peptide for the Treatment and Mechanism of Diabetic Infected Wounds

Journal of Diabetes Research
Diabetic wounds, due to severe vascular dysfunction, persistent inflammatory responses, and susceptibility to microbial infections, exhibit delayed healing and pose a significant challenge to human health.
Rongqin Feng, Peng Wang, Li Fan, He Lu, Danna Yao, Panpan Sun, Zhonghua Liu, Fu Han, Xiaozhi Bai, Xuekang Yang, Juntao Han   +10 more
doaj   +1 more source

Re-biopsy of partially sampled thin melanoma impacts sentinel lymph node sampling as well as surgical margins

Melanoma Management, 2019
Aim: To assess the impact of re-biopsy on partially sampled melanoma in situ (MIS), atypical melanocytic proliferation (AMP) and thin invasive melanoma.
Evan S Weitman, Matthew C Perez, Daniel Lee, Youngchul Kim, William Fulp, Vernon K Sondak, Amod A Sarnaik, Ricardo J Gonzalez, Carl W Cruse, Jane L Messina, Jonathan S Zager   +10 more
doaj   +1 more source