Results 181 to 190 of about 2,820,921 (304)

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Clinical and immunological markers of peanut allergy severity and tolerance in children. [PDF]

Front Allergy
Petek T, Koren B, Tomazin M, Hojnik T, Berce V, Lajhar M, Krašovec B, Homšak M, Skerbinjek Kavalar M, Korošec P.   +9 more
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Evaluating a virtual paediatric adverse drug reaction clinic

British Journal of Clinical Pharmacology, EarlyView.
Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck, Blanca Del Pozzo‐Magana, Michael Rieder   +2 more
wiley   +1 more source

Immunoglobulin Light Chain Amyloidosis. [PDF]

Clin Case Rep
Lyon J, Khouri A, Bell KA, Zussman J.
europepmc   +1 more source

Cutaneous Vasoconstriction Affects Near-infrared Spectroscopy Determined Cerebral Oxygen Saturation during Administration of Norepinephrine

Anesthesiology, 2012
H. Sørensen, N. Secher, Christoph Siebenmann, H. Nielsen, M. Kohl-Bareis, C. Lundby, P. Rasmussen   +6 more
semanticscholar   +1 more source

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

British Journal of Clinical Pharmacology, EarlyView.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis, Kailey Tang, Renee Dimond, Alice Lei, Amanda Wilkins, Amanda Gwee   +5 more
wiley   +1 more source

Annular Cutaneous Pili Migrans on the Scrotum: A Rare Clinical Presentation. [PDF]

Clin Case Rep
Yang J, Hui H.
europepmc   +1 more source

Lost and found in translation: the value of the human imiquimod model

British Journal of Clinical Pharmacology, EarlyView.
Topical imiquimod (IMQ), a Toll‐like receptor (TLR) 7 agonist, induces transient cutaneous inflammation and is widely used in preclinical research as a ‘psoriasis‐like’ mouse model. However, accumulating evidence indicates substantial divergence between IMQ‐driven biology and human plaque psoriasis pathogenesis.
Anouk C. Meijs, Juliette A. van den Noort, Salma Assil, Naomi B. Klarenbeek, Matthijs Moerland, Tessa Niemeyer‐van der Kolk, Robert Rissmann   +6 more
wiley   +1 more source

Harnessing skin-resident γδ T cells for immunotherapy in cutaneous squamous cell carcinoma. [PDF]

Sci Adv
Nasi G, Schöftner LC, Ronacher L, Sophianidis A, Feiser J, Aleksandrova T, Nussbaumer O, Hutton A, Zauner R, Moser-Waxenecker J, Varkhande SR, Sharma A, Ettinger M, Burner T, Laimer M, Guttmann-Gruber C, Gratz IK.   +16 more
europepmc   +1 more source