Results 101 to 110 of about 2,458,206 (306)

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Intraperitoneal Administration as an Alternative to Intravenous for Classical Antitumor Cytostatics at the Preclinical Stage of Study

Антибиотики и Химиотерапия
Background. Intraperitoneal administration of drugs is a common practice in preclinical studies using laboratory animals. The distinctive features of the intraperitoneal route of administration are ease to master, simplicity of execution, as well as the ...
M. I. Treshchalin, V. A. Polozkova, S. G. Yazeryan, M. S. Kalishyan, E. R. Pereverzeva   +4 more
doaj   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Prevalence of intravenous medication administration errors: a cross-sectional study

, 2017
Tezeta Fekadu,1 Mebrahtu Teweldemedhin,2 Eyerusalem Esrael,1 Solomon Weldegebreal Asgedom1 1School of Pharmacy, Department of Clinical Pharmacy, College of Health Sciences, Mekelle University, Mekelle, 2Unit of Biomedical Science, School of Medicine ...
Teweldemedhin M, Esrael E, Asgedom SW, Fekadu T   +3 more
core  

The effect of excipients on pharmacokinetic parameters of parenteral drugs [PDF]

, 2005
In the pharmaceutical industry, the main goal of early phase in vivo studies is to assess pharmacokinetic properties of a compound in laboratory animals. These data provide a basis for selecting and optimizing drug candidates.
Egger-Heigold, Barbara
core   +1 more source

IV-EVE: EVE for Injection—ADME, Pharmacokinetic and Toxicological Evaluation for Novel Deciparticle EVE Formulation

Biomedicines
Background: Oral everolimus (Oral-EVE; EVE, Afinitor®) is an effective therapy for multiple malignancies, including HR-positive/HER2-negative breast cancer, but its clinical use is limited by low and variable oral bioavailability as well as extensive ...
Wen-Han Chang, Nancy Chang, Sheng-Hao Min, John M. Lopp, Robert Hoff, Tanjina Hoque, Vuong Trieu, Cynthia Lee   +7 more
doaj   +1 more source

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

Arthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper, Rachel Black, Joanna Tieu, Winnie Chen, Matthew Parker, Catherine Hill, Natasha Nassar, Mandana Nikpour   +7 more
wiley   +1 more source

Ultrasound evaluation of peripheral intravenous catheter thrombus formation associated with intravenous flucloxacillin administration: A prospective observational pilot study

Purpose The purpose of this study was to sonographically evaluate whether intravenous (IV) flucloxacillin administration was associated with an increased risk of peripheral intravenous catheter (PIVC) thrombus formation. Methods This observational study
Keijzers, Gerben, Snelling, Peter J, Nightingale, Rachael, Bulmer, Andrew C, Hewage, Wenu   +4 more
core   +1 more source

Long-term intravenous administration of carboxylated single-walled carbon nanotubes induces persistent accumulation in the lungs and pulmonary fibrosis via the nuclear factor-kappa B pathway

, 2016
Yue Qin,1,* Suning Li,2,* Gan Zhao,2,* Xuanhao Fu,1 Xueping Xie,1 Yiyi Huang,1 Xiaojing Cheng,3 Jinbin Wei,1 Huagang Liu,1 Zefeng Lai1 1Pharmaceutical College, Guangxi Medical University, 2Department of Pharmacy, The Maternal and Child Health Hospital ...
Liu H, Lai Z, Li S, Huang Y, Xie X, Fu X, Zhao G, Qin Y, Wei J, Cheng X   +9 more
core  

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source