Results 121 to 130 of about 550,133 (313)

Cerebral blood flow effects of acute intravenous heroin administration

, 2008
We examined acute effects of intravenous diacetylmorphine (heroin) administration - which induces a characteristic biphasic response: A short rush-sensation associated with intense pleasurable feelings followed by a subjectively different period of ...
Hämmig, Robert, Bundeli, P, Kayser, Sarah, Brenneisen, R, Schlaepfer, T.E., Wielepp, P, Heidbreder, Rebeca, Kosel, M, Heidbreder, R, Kinser, J.A., Brenneisen, Rudolf, Wielepp, Peter, Hämmig, R, Noss, Roger S., Noss, R.S., Kayser, S, Bundeli, Petra, Fisch, H.U., Kosel, Markus Mathaus, Schlaepfer, Thomas E., Kinser, Jane A., Fisch, Hans-Ulrich   +21 more
core   +1 more source

Evaluating the safety, pharmacokinetics and efficacy of phage therapy in treating fracture-related infections with multidrug-resistant Staphylococcus aureus: intravenous versus local application in sheep

Frontiers in Cellular and Infection Microbiology
BackgroundFracture-related infections (FRI), particularly those caused by antibiotic resistant Staphylococcus aureus, present significant clinical challenges due to the formation of biofilm on the implanted device, and reduced options for conventional ...
Christian Peez, Christian Peez, Baixing Chen, Baixing Chen, Baixing Chen, Leopold Henssler, Leopold Henssler, Marco Chittò, Jolien Onsea, Jolien Onsea, Michael H. J. Verhofstad, Daniel Arens, Caroline Constant, Stephan Zeiter, William Obremskey, Andrej Trampuz, Michael J. Raschke, Charalampos Zalavras, Willem-Jan Metsemakers, Willem-Jan Metsemakers, T. Fintan Moriarty   +20 more
doaj   +1 more source

Pharmacokinetics of Luteolin and Metabolites in Rats

Natural Product Communications, 2008
The pharmacokinetic parameters of luteolin and its glucuronide/sulfate conjugates were studied in rats after a single 50 mg/kg dose of luteolin administered as intravenous bolus or oral solution.
Sasiporn Sarawek, Hartmut Derendorf, Veronika Butterweck   +2 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Delivery of the vitamin E compound tocotrienol to cancer cells

, 2011
Tocotrienol, a member of the vitamin E family of compounds, is currently receiving increased attention because of its highly promising anti-cancer effects.
Dufès, Christine
core  

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats

, 2003
The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Dufès, Christine, Couet, William, Olivier, Jean-Christophe, Gaillard, Frédéric, Gaillard, Afsaneh, Muller, Jean-Marc   +5 more
core   +1 more source

In the preparation and administration of intravenous medicines, what are the best practice standards that healthcare professionals need to follow to ensure patient safety? Protocol for a systematic review.

, 2020
Introduction: Intravenous therapy and medicines (IVTM) are the most common invasive interventions in use in healthcare. Prescribed IVTM play an essential role in the treatment of illness, management of chronic conditions and in maintaining health and ...
O'Toole, Orla, Laura O'Connor, O'Hara, Paul, Patricia Healy, Ivory, John D, Carr, Peter J, Orla O'Toole, Healy, Patricia, O'Connor, Laura, Peter J. Carr, Paul O'Hara, Georgina Gethin, John D. Ivory, Gethin, Georgina   +13 more
core   +1 more source

Intraoperative administration of intravenous flurbiprofen axetil with nalbuphine reduces postoperative pain after orbital decompression: a single-center, prospective randomized controlled trial

, 2019
Huijing Ye,* Xiufen Lian,* Rongxin Chen, Yanling Zhu, Hongbin Chen, Jingxia Huang, Ling Xie, Wenfang Ma, Huasheng Yang, Wenjun Guo State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China *These ...
Yang H, Zhu Y, Huang J, Lian X, Guo W, Xie L, Chen H, Ye H, Chen R, Ma W   +9 more
core  

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study from the EUSTAR Cohort

Arthritis Care &Research, Accepted Article.
Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P Denton, Madelon C Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source