Results 131 to 140 of about 550,133 (313)

Optimal timing for intravenous administration set replacement

, 2005
Background Administration of intravenous therapy is a common occurrence within the hospital setting. Routine replacement of administration sets has been advocated to reduce intravenous infusion contamination.
Wallen, M, Morrison, A, Gillies, D, Rankin, K, O'riordan, L, Nagy, SA   +5 more
core  

The burden of systemic therapy administration route in treating HER2-positive breast cancer (for patients, healthcare professionals, and healthcare system): a systematic literature review

Frontiers in Pharmacology
IntroductionBreast cancer (BC) is one of the leading causes of cancer and is the first cause of death from malignant tumors among women worldwide. New cancer therapies receive regulatory approval yearly and to avoid health disparities in society, the ...
Luciana Castro Garcia Landeiro, Tamie de Camargo Martins, Ruth Bartelli Grigolon, Isabel Monteiro, Joana Bisol Balardin, Eduardo Padilha, Gilberto Amorim, Stephen Stefani   +7 more
doaj   +1 more source

Intravenous administration of colchicine [PDF]

Arthritis & Rheumatism, 1981
openaire   +2 more sources

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

Advanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang, Kailin Mooney, Mingchong Dai, Morgan R. Stewart, Samantha Holland, Michael I. Henderson, Samuel Drennan, Ramon F. Barajas Jr., Jared M. Fischer, Adem Yildirim   +9 more
wiley   +1 more source

Interruptions during intravenous medication administration: a multicenter observational study.

, 2019
Aims To determine the frequency and cause of interruptions during intravenous medication administration, which factors are associated with interruptions and to what extent interruptions influence protocol compliance.
Bruijne, M.C. de, Schutijser, B.C.F.M., Wagner, C., Klopotowska, J.E., Jongerden, I.P., Spreeuwenberg, P.M.M.   +5 more
core  

Clinical Use of Intravenous Iron: Administration, Efficacy, and Safety

, 2010
This section reviews the history, pharmacology, administration, efficacy, and toxicity of intravenous iron. Intravenous iron offers advantages over oral iron for the treatment of iron deficiency anemia across a wide range of disease states associated ...
Michael Auerbach, Harold Ballard
core   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Pharmacokinetics of SNF472 after intravenous (A, B) and subcutaneous (C, D) bolus administration and intravenous infusion into rats (E-G).

, 2018
Phytate levels quantified in plasma samples of control Wistar rats after intravenous (A) and subcutaneous (C) bolus administration (N = 3) and in control and uremic Wistar rats after intravenous infusion of 10 mg/kg (E) and 50 mg/kg SNF472 (F) (N = 5 ...
Geert J. Behets (630682), Eva Tur (5194457), Pieter H. Joubert (5194460), Ellen Neven (630677), Carolina Salcedo (2497255), Fernando Tur (2466883), Bernat Isern (790350), Patrick C. D’Haese (700370), Miguel D. Ferrer (3279351), Markus Ketteler (3756307), Joan Perelló (311612)   +10 more
core   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source