Results 71 to 80 of about 908,314 (313)

Alternative treatments for oral bisphosphonate-related osteonecrosis of the jaws: a pilot study comparing fibrin rich in growth factors and teriparatide [PDF]

, 2014
Objectives: The aim of this study is to describe and compare the evolution of recurrent bisphosphonate-related osteonecrosis of the jaws (BRONJ) in patients treated with plasma rich in growth factors or teriparatide.
Pelaz García, Alejandro, Gómez Alonso, C., García-Consuegra, L., Gómez Alonso, Carlos, García-Consuegra Gómez del Pulgar, Luis Fernando, Junquera, Sonsoles, Gallego, Lorena, Pelaz, A., Gallego López, Lorena, Junquera Gutiérrez, Luis Manuel   +9 more
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IMMUNOLOGIC PREVENTION OF IDDM BY ORAL ADMINISTRATION OF GLUTAMIC ACID DECARBOXYLASE [PDF]

Acta Medica Iranica, 1999
We have Investigated the preventive effects of oral administration of isolated E.coli ghttam'tc acid decarboxylase (GAD) in animal models. Based on our results, the blood glucose levels were reduced by oral administration of GAD to rats 14 days before ...
L. Yazdchi Mari, Sh. Rajieii. R. Yazdanparast   +1 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Cost-minimization analysis of oral and intravenous administration of linezolid in a public hospital in southern Brazil

Revista de Ciências Farmacêuticas Básica e Aplicada, 2015
Due to the paucity of cost-minimization studies about linezolid, the aim of this study was to estimate the cost differential between intravenous and oral administration.
Érika Taguti, Edson Antonio Alves da Silva, Andréia Cristina Conegero Sanches   +2 more
doaj  

Oral esketamine for treatment-resistant depression: rationale and design of a randomized controlled trial

BMC Psychiatry, 2019
Background There is an urgent need to develop additional treatment strategies for patients with treatment-resistant depression (TRD). The rapid but short-lived antidepressant effects of intravenous (IV) ketamine as a racemic mixture have been shown ...
Sanne Y. Smith-Apeldoorn, Jolien K. E. Veraart, Jeanine Kamphuis, Antoinette D. I. van Asselt, Daan J. Touw, Marije aan het Rot, Robert A. Schoevers   +6 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Liposomal-encapsulated Ascorbic Acid: Influence on Vitamin C Bioavailability and Capacity to Protect against Ischemia–Reperfusion Injury

Nutrition and Metabolic Insights, 2016
Intravenous administration of vitamin C has been shown to decrease oxidative stress and, in some instances, improve physiological function in adult humans.
Janelle L. Davis, Hunter L. Paris, Joseph W. Beals, Scott E. Binns, Gregory R. Giordano, Rebecca L. Scalzo, Melani M. Schweder, Emek Blair, Christopher Bell   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Oral history interview with Paige White [PDF]

, 2020
Paige White recounts her experience walking from Tulsa to OKC. She discusses the emotional experiences along the way, both positive and negative, and the effect of the relationships formed.
White, Paige
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