Results 61 to 70 of about 4,084,506 (304)
The Oral Administration Of Antitoxins [PDF]
Journal of Infectious Diseases, 1909 This paper is a report of the later results of a series of investigations which were published in this Journal1 in 1906. At that time our results warranted us in concluding that diphtheria and tetanus antitoxins, when given per mouth to experimental animals, were absorbed in sufficient quantities to protect those animals against several fatal doses of ...
McClintock, C. T., King, W. E.
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Pharmacokinetics and thermal anti-nociceptive effects of oral morphine in horses
Frontiers in Veterinary ScienceIntroductionMorphine is an effective analgesic in horses, however, IV administration at therapeutic doses has been shown to produce dose-dependent neuroexcitation and unwanted gastrointestinal effects.
Heather K. Knych +5 more
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Use of Mifepristone and Sublingual Misoprostol for Early Medical Abortion
Taiwanese Journal of Obstetrics & Gynecology, 2006 Objective: Existing drug-induced abortion techniques involve oral administration of 200 mg of mifepristone, followed by oral administration of 600 mg of misoprostol 48 hours later, but the effects are variable.
Mau Lin +6 more
doaj +1 more source
Guidelines for the administration of oral examinations
Saudi Medical Journal, 2000 Practical oral examinations are considered an important and often a difficult part of medical school examinations. They represent an accurate and direct mean of assessing student9s interaction with patients and their clinical and technical skills. This paper reviews an outline for the administration of oral examinations.
M M, Jan, A R, Al-Buhairi
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Revista de Ciências Farmacêuticas Básica e Aplicada, 2015 Due to the paucity of cost-minimization studies about linezolid, the aim of this study was to estimate the cost differential between intravenous and oral administration.
Érika Taguti +2 more
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
IMMUNOLOGIC PREVENTION OF IDDM BY ORAL ADMINISTRATION OF GLUTAMIC ACID DECARBOXYLASE [PDF]
Acta Medica Iranica, 1999 We have Investigated the preventive effects of oral administration of isolated E.coli ghttam'tc acid decarboxylase (GAD) in animal models. Based on our results, the blood glucose levels were reduced by oral administration of GAD to rats 14 days before ...
L. Yazdchi Mari +1 more
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BMC Psychiatry, 2019 Background There is an urgent need to develop additional treatment strategies for patients with treatment-resistant depression (TRD). The rapid but short-lived antidepressant effects of intravenous (IV) ketamine as a racemic mixture have been shown ...
Sanne Y. Smith-Apeldoorn +6 more
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