Results 41 to 50 of about 908,314 (313)

Enhanced Bioavailability of Tadalafil after Intranasal Administration in Beagle Dogs

Pharmaceutics, 2018
Tadalafil is an oral selective phosphodiesterase type-5 inhibitor with demonstrated efficacy and safety that is used to treat erectile dysfunction. The purpose of this study is to compare the pharmacokinetic properties of tadalafil after conventional ...
Jeong-Soo Kim, Min-Soo Kim, In-hwan Baek
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Designing and implementing a real estate appraisal system: the case of Québec Province, Canada [PDF]

, 2015
Due to copyright restrictions, the access to the full text of this article is only available via subscription.Real estate appraisal is of great importance to several socio-economic stakeholders for different reasons and justifications: local governments ...
Kettani, O., Oral, Muhittin
core   +1 more source

Pharmacokinetic Interaction Between Oltipraz and Silymarin in Rats

Journal of Pharmacy & Pharmaceutical Sciences, 2009
. Purpose: To evaluate the pharmacokinetic interaction between oltipraz and silymarin after intravenous and oral administration of both drugs to male Sprague–Dawley rats.
Min Kyung Kang, Soo Kyung Bae, Jin Wan Kim, Myung Gull Lee   +3 more
doaj   +1 more source

Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice and Rats

Pharmaceutics, 2022
This study investigated the pharmacokinetics and tissue distribution of enavogliflozin, a novel sodium-glucose cotransporter 2 inhibitor that is currently in phase three clinical trials.
Minyeong Pang, So Yeon Jeon, Min-Koo Choi, Ji-Hyeon Jeon, Hye-Young Ji, Ji-Soo Choi, Im-Sook Song   +6 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Oral administration of PET tracers: Current status [PDF]

, 2023
The oral route is the most widely used and preferable way of drug administration. Several pharmacokinetic processes play a role in the distribution of administered drugs.
Charalampos Tsoumpas, Mantovani, Dimitri B. A., Pascalle Mossel, Ana Maria Marques da Silva, Gert Luurtsema, Salvi de Souza, Giordana, Boersma, Hendrikus H., Dimitri B.A. Mantovani, Boersma, Hendrikus H.; id_orcid, Lammertsma, Adriaan A., Tsoumpas, Charalampos, Bartholomeus C.M. Haarman, Haarman, Bartholomeus C.M., Haarman, Bartholomeus C.M.; id_orcid, Silva, Ana Maria Marques da, Hendrikus H. Boersma, Mantovani, Dimitri B.A., Haarman, Bartholomeus C. M., Marques da Silva, Ana Maria, Cristiane R.G. Furini, Mossel, Pascalle; id_orcid, Furini, Cristiane R.G., Tsoumpas, Charalampos; id_orcid, Mossel, Pascalle, Souza, Giordana Salvi de, Furini, Cristiane R. G., Adriaan A. Lammertsma, Luurtsema, Gert, Salvi de Souza, Giordana ; id_orcid, Giordana Salvi de Souza   +29 more
core   +1 more source

A Comparative Pharmacology Study Between the Intracolonic and Oral Routes of 5-FU Administration in a Colon Cancer-Bearing Yoshida Sarcoma Rat Model

Journal of Pharmacological Sciences, 2004
We prepared a colon cancer-bearing Yoshida sarcoma rat model to examine the dose-response relationship of antitumor activity of intracolonically or orally administered 5-fluorouracil (5-FU; 45, 30, 20, 13, and 8 mg/kg).
Takeshi Goto, Naoko Tomizawa, Eiji Kobayashi, Akio Fujimura   +3 more
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K-1) in severe acute liver disease [PDF]

, 2005
Background/Aims: In patients with severe acute liver dysfunction, i.v. phylloquinone (vitamin K-1) may be given to exclude vitamin K deficiency, rather than impaired hepatic synthesis of coagulation factors alone, as the cause of the coagulopathy ...
Pereira, SP, David Rowbotham, Stephen P. Pereira, Sarah Fitt, Fitt, S, Pereira, S P, Wendon, J, Roger Williams, Williams, R, Julia Wendon, Rowbotham, D, Martin J. Shearer, Shearer, MJ, Shearer, M J   +13 more
core   +1 more source