Results 41 to 50 of about 903,930 (312)

Effects of BCL oral administation and herbal acupuncture at BL18, BL19 on Liver function changes induced by Alcohol in the mice

Journal of Pharmacopuncture, 2002
This dissertation was designed to evaluate the effect of BCL(refinded Bambusae Caulis in Liqua-men) oral administration and herbal acupuncture on alcohol metabolism and liver function. For this study.
Sa-Hyun Park
doaj   +1 more source

Pharmacokinetic behavior of gentiopicroside from decoction of radix gentianae, gentiana macrophylla after oral administration in rats: a pharmacokinetic comaprison with gentiopicroside after oral and intravenous administration alone

, 2007
The pharmacokinetics in rats of gentiopicroside (GPS) from orally administered decoctions ofRadix Gentianae (DRG) andGentiana macrophlla (DGM) were compared with that of GPS alone administered at 150 mg/kg orally and 30 mg/kg intravenously. The metabolic
Cheng, X.M., Wang, C.-H., Branford-White, C.J., He, Y.Q., White, K.N., Wang, Z., Bligh, S.W.A.   +6 more
core   +1 more source

Methotrexate efficacy and tolerability after switching from oral to subcutaneous route of administration in juvenile idiopathic arthritis

Rheumatology, 2016
Objectives : Methotrexate (MTX) is one of the most frequently used, highly effective disease-modifying drugs in juvenile idiopathic arthritis (JIA) therapy.
Zbigniew Żuber, Dorota Turowska-Heydel, Małgorzata Sobczyk, Marta Banach-Górnicka, Katarzyna Rusnak, Anna Piszczek, Elżbieta Mężyk   +6 more
doaj   +1 more source

Oral testosterone self-administration in male hamsters

, 2001
The addiction potential of anabolic steroids remains largely unexplored. Here, we demonstrate voluntary oral testosterone intake in hamsters. Using a 2-bottle choice test, males preferred an aqueous solution of 200 microg/ml testosterone over vehicle ...
Wood, R.I., Johnson, L.R.
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Enhanced Bioavailability of Tadalafil after Intranasal Administration in Beagle Dogs

Pharmaceutics, 2018
Tadalafil is an oral selective phosphodiesterase type-5 inhibitor with demonstrated efficacy and safety that is used to treat erectile dysfunction. The purpose of this study is to compare the pharmacokinetic properties of tadalafil after conventional ...
Jeong-Soo Kim, Min-Soo Kim, In-hwan Baek
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Oral administration of PET tracers: Current status [PDF]

, 2023
The oral route is the most widely used and preferable way of drug administration. Several pharmacokinetic processes play a role in the distribution of administered drugs.
Charalampos Tsoumpas, Mantovani, Dimitri B. A., Pascalle Mossel, Ana Maria Marques da Silva, Gert Luurtsema, Salvi de Souza, Giordana, Boersma, Hendrikus H., Dimitri B.A. Mantovani, Boersma, Hendrikus H.; id_orcid, Lammertsma, Adriaan A., Tsoumpas, Charalampos, Bartholomeus C.M. Haarman, Haarman, Bartholomeus C.M., Haarman, Bartholomeus C.M.; id_orcid, Silva, Ana Maria Marques da, Hendrikus H. Boersma, Mantovani, Dimitri B.A., Haarman, Bartholomeus C. M., Marques da Silva, Ana Maria, Cristiane R.G. Furini, Mossel, Pascalle; id_orcid, Furini, Cristiane R.G., Tsoumpas, Charalampos; id_orcid, Mossel, Pascalle, Souza, Giordana Salvi de, Furini, Cristiane R. G., Adriaan A. Lammertsma, Luurtsema, Gert, Salvi de Souza, Giordana ; id_orcid, Giordana Salvi de Souza   +29 more
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Pharmacokinetic Interaction Between Oltipraz and Silymarin in Rats

Journal of Pharmacy & Pharmaceutical Sciences, 2009
. Purpose: To evaluate the pharmacokinetic interaction between oltipraz and silymarin after intravenous and oral administration of both drugs to male Sprague–Dawley rats.
Min Kyung Kang, Soo Kyung Bae, Jin Wan Kim, Myung Gull Lee   +3 more
doaj   +1 more source