Oral drug administration to pediatric patients is characterized by a lack of age-appropriate drug products and the off-label use of medicines. However, drug administration practices at hospital wards is a scarcely studied subject.
Maria Rautamo +5 more
doaj +1 more source
Oral testosterone self-administration in male hamsters [PDF]
The addiction potential of anabolic steroids remains largely unexplored. Here, we demonstrate voluntary oral testosterone intake in hamsters. Using a 2-bottle choice test, males preferred an aqueous solution of 200 microg/ml testosterone over vehicle ...
Wood, R.I., Johnson, L.R.
core +1 more source
Development of a high-speed MALDI-triple quadrupole mass spectrometric method for the determination of 3,4-methylenedioxymethamphetamine (MDMA) in oral fluid [PDF]
3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is still a widely used illicit designer drug and its detection in different matrices is of major importance for forensic purposes (e.g.
Hysek, Cédric M +12 more
core +1 more source
No relation between docetaxel administration route and high‐grade diarrhea incidence
Oral administration of docetaxel in combination with the CYP3A4 inhibitor ritonavir is used in clinical trials to improve oral bioavailability of docetaxel. Diarrhea was the most commonly observed and dose‐limiting toxicity.
Jeroen J. M. A. Hendrikx +9 more
doaj +1 more source
Pharmacokinetic Model Analysis of Supralingual, Oral and Intravenous Deliveries of Mycophenolic Acid
Mycophenolic acid (MPA) is commonly used for organ rejection prophylaxis via oral administration in the clinic. Recent studies have shown that MPA also has anticancer activities. To explore new therapeutic options for oral precancerous/cancerous lesions,
Xiuqing Gao +7 more
doaj +1 more source
Oral Administration of Bacitracin
SummaryFrom the small series of animals receiving oral bacitracin, the following significant facts were obtained: 1. Fecal streptococci and spore forming anaerobes were greatly reduced in the intestine at a dosage between 2,000 and 10,000 u/kg per day. 2. Coliform organisms were little affected by bacitracin. 3.
G. C. Bond +3 more
openaire +2 more sources
Pharmacokinetics and concentration-effect relationship of oral LSD in humans [PDF]
BACKGROUND: The pharmacokinetics of oral lysergic acid diethylamide are unknown despite its common recreational use and renewed interest in its use in psychiatric research and practice.
Dolder, Patrick C. +4 more
core +1 more source
Comparison of the Effect of Oral Versus Intravenous Bisphosphonate Administration on Osteoclastogenesis in Advanced-Stage Medication-Related Osteonecrosis of the Jaw Patients [PDF]
It is yet unknown whether the intravenous administration route alone can fully account for the exacerbation of medication-related osteonecrosis of the jaw (MRONJ).
Min-Woo Lee +3 more
core +1 more source
The effects on postoperative oral surgery pain by varying NSAID administration times: Comparison on effect of preemptive analgesia [PDF]
OBJECTIVE: Many studies on the efficacy of preemptive analgesia have been processed in different ways. But the value of preemptive analgesia is still controversial.
박형식 +3 more
core +1 more source
Comparison of the self-administered and interviewer-administered modes of the child-OIDP [PDF]
Background: The mode of questionnaire administration may affect the estimates and applicability of oral health-related quality of life indicators. The aim of this study was to compare psychometrically the self-administered Child-OIDP index with the ...
O'Brien Kevin +19 more
core +1 more source

